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| Biological Chemistry Division | |||||
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The research focus of the Biological Chemistry Division is to explore the structure and function of proteins by an integrated approach involving biophysical, biochemical, cell and molecular biological methodologies bringing together several groups of researchers with adequate and complementary expertises in these areas. Read more about the Biological Chemistry Division on the ITQB Annual Report. Our
activities broadly cover the following areas; a) Sulphate and oxygen
respiration, b) NO metabolism and signalling, c) Oxidative, metals and
metalloid stresses, d) Protein Structure, foldingand stability, e)
Protein Modelling, and f) Proteins in Biotechnology. The groups
belonging to this division are listed below. |
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| Laboratory | Laboratory Leader | Scientific Area (keywords) | |||
| Genomics and Stress Laboratory | Claudina R. Pousada |
Gene expression; Stress;Yeast; Desulfovibrio gigas; Genome; Metalloproteins | |||
| Inorganic Biochemistry and NMR | Ricardo O. Louro |
Metalloproteins; Structure-function relationship; Metal-microbe interactions | |||
| Membrane Protein Crystallography | Margarida Archer |
Crystallography; Membrane Proteins; Drug design; Biomedical interest | |||
| Metalloproteins and Bioenergetics | Miguel Teixeira | Energy transduction/membrane proteins ; Superoxide and NO detoxification; eT metalloenzymes | |||
| Microbial Biochemistry | Inês A. Cardoso Pereira | Sulfate Reducing Bacteria; Anaerobic respiration | |||
| Microbial & Enzyme Technology | Ligia O. Martins | Bacterial
laccases; Enzyme engineering; Applied biocatalysis |
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| Molecular
Genetics of Metalloproteins |
Ligia M. Saraiva |
Gene
Expression; Regulation; Nitric Oxide; Sulfate Reducing Bacteria;
Enterobacteriaceae |
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| Molecular
Simulation |
Antonio M. Baptista |
Theoretical/computational
methods; Protein electrostatics; pH/redox
effects |
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| Protein Biochemistry, Folding & Stability | Claudio M. Gomes |
Cofactors and
stability; Thermophilic proteins; Folding and Disease |
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| Protein Crystallography | Maria Armenia Carrondo |
Metalloproteins; Proteins with biomedical applications | |||
| Protein Modelling | Claudio M. Soares |
Structural Bioinformatics; Molecular mechanisms; Redox Proteins | |||