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[SCAN] Insertion sequences as key players in phenotypic and genotypic plasticity of Staphylococcus haemolyticus

Filed under:

Ons Bouchami, Bacterial Evolution and Molecular Epidemiology, ITQB NOVA

When 19 Apr, 2017 from
12:00 pm to 01:00 pm
Where Auditorium
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Title: Insertion sequences as key players in phenotypic and genotypic plasticity of Staphylococcus haemolyticus

Speaker: Ons Bouchami

Affiliation: Maria Miragaia Lab - Bacterial Evolution and Molecular Epidemiology

 

Abstract:

Staphylococcus haemolyticus is nowadays recognized as one of the most important nosocomial human pathogens worldwide, mainly associated to medical device-related infections. Our most recent approaches using whole genome sequencing have shown that cell populations of these bacteria suffer frequently phenotypic variation and genome rearrangements promoted by the activity of insertion sequences (IS) elements. The maintenance of subpopulations of cells in different physiological states might be a strategy to adapt rapidly to environmental stresses imposed by host or hospital environment.

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