Financed Projects
Financed projects:
2012 – 2015 - “A novel generation of packaging cell lines for the manufacture of lentivirus based biopharmaceuticals” - PTDC/EBB-BIO/118615/2010, funded by FCT.
2012 – 2015 - “Development of improved suspension MDCK cell lines for the production of viral based bioproducts: manufacturing Influenza and Adenovirus” - PTDC/EBB-EBI/118621/2010, funded by FCT.
2012 – 2015 - “Human central nervous system in vitro models for preclinical research: new tools for studying viral vector-mediated gene” - PTDC/EBB-BIO/119243/2010, funded by FCT.
2012 – 2015 - “Probing adenovirus-host cell interactions: a systems biotechnology approach to improve production of gene delivery vectors” - PTDC/EBB-BIO/119501/2010, funded by FCT.
2012 – 2014 - “SpeCCC - Specialised Cell Carrier Components” FP7‐SME‐2012‐315717, funded by EU.
2011 – 2014 - “NanoGene - Stem cell generation and manipulation by nanoparticle mediated gene transfer for the safe clinical application of gene-modified cells” – ENMED/0001/2010, financed by the EuroNanoMed ERA-Net Initiative.
2011 – 2015 “ComplexINC “- New Technologies and Production Tools for Complex Protein Biologics. FP7 / SME-targeted research for developing tools and technologies for high-throughput research, funded by EU. http://eurice.eu/projects/life-sciences/complexinc/
2011-2016 - "PREDECT” – New Models for Preclinical Evaluation of Drug Efficacy in common solid tumours" - GRANT AGREEMENT No. 115188, funded by IMI (Innovative Medicines Initiative) Joint Undertaking, funded by EU. www.predect.eu
2011-2014 - "3D in vitro models for reducing animal experimentation in pharmaceutical development: integrative approaches for prediction of hepatic drug metabolism and neurotoxicity" - PTDC/EBB-BIO/112786/2009, funded by FCT
2010 – 2015 - “Cardio Repair European Multidisciplinary Initiative” - HEALTH-F5-2010-242038, funded by EU
2010 – 2012– “2D fluorometry: a powerful tool to improve mammalian cell process development” - PTDC/EBB-EBI/102750/2008, funded by FCT
2010-2012 – “Novel Cell Factories for the production of secreted complex bioproducts: a syntetic biology approach for improved product Stoichiometries” - PTDC/EBB-EBI/102266/2008, funded by FCT
2010-2012 – “BACULOME-Engineering cellular energetics for improvement of bioprocesses: metabolic modeling for enhanced vaccines production” - PTDC/EBB-EBI/103359/2008, funded by FCT
2010-2012 - “Retroviral like particles: improving potential as candidate vaccines for Hepatitis C” - PTDC/EBB-BIO/102649/2008, funded by FCT
2010-2012 – “Using functional genomics to improve mammalian cells for virus based biopharmaceuticals manufacture” - PTDC/EBB-BIO/100491/2008, funded by FCT
2010-2012 – “Preconditioning triggered by Carbon monoxide: new strategies to prevent brain damage due to hypoxia-ischemia and reperfusion” - PTDC/SAU-NEU/098747/2008, funded by FCT
2009-2012 - "HYPERLAB - high yield and performance stem cell lab", funded by EU (223011)
2009-2012 - "Integrated strategies for expansion, neuronal differentiation and cryopreservation of human embryonic stem cells", funded by FCT (PTDC/BIO/72755/2006)
2008-2012 - "BrainCAV: Gene Transfer for Brain Therapy", funded by EU (FP7-222992)
2007-2010 - "Fundamentals of downstream processing of enveloped viruses: towards an integration of purification processes", funded by FCT (PTDC/EQU-EQU/71645/2006)
2006-2011 - "CLINIGENE-NoE: European Network for the Advancement of Clinical Gene Transfer and Therapy", funded by EU (LSHB-CT-2006-018933)
2007-2010 - "Manufacturing canine adenovirus vectors for gene therapy: development of MDCK CAV-2E1- transcomplementing cell lines", funded by FCT (PTDC/BIO/69452/2006)
2007-2010 - "Development of flexible cell lines for the Production of Retrovirus and Lentivirus for Gene Therapy", funded by FCT (PTDC/BIO/69451/2006)
2007-2010 - "Novel stroke model for neuroprotective research: bioreaction of primary brain cell aggregates", funded by FCT (PTDC/BIO/69407/2006)
2007-2010 - “Carbon monoxide as a neuroprotective agent against hypoxia-ischemia and reperfusion”, funded by FCT, Portugal (PTDC/SAU-NEU/64327/2006)
2006-2009 - "Reducing Animal Experimentation in Preclinical Predictive Drug Testing by Human Hepatic in vitro Models Derived from Embryonic Stem Cells", funded by EU (LSHB-CT-2006-018940)
2006-2009 - "BACULOGENES – Baculovirus Vectors for Gene Therapy", funded by EU (FP6 - 2007)
2004-2009 - "Cell Programming by Nanoscaled Devices", funded by EU (NMP4-CT-2004-500039)
2005-2007 - "Advanced Control of BHK Cultivation Processes Based on Intracellular Metabolic Fluxes", funded by FCT, Portugal (POCI/BIO/57927/2004)
2005-2007 - "THERAVECT, Production, Purification and Storage of Retroviral Vectors Produced by Modular Master Producer Cells", funded by FCT, Portugal (010.6/A003/2005)
2005-2007 - "CELL CRYOTHERA: Cell Cryopreservation for Therapy and Regenerative Medicine", funded by FCT, Portugal (010.6/A006/2005)
2005-2007 - "Development of marker vaccines, companion diagnostic tests and improvement of epidemiological knowledge to facilitate control of rinderpest and peste des petits ruminants viruses", funded by EU (RP/PPR MARKVAC)
2005-2007 - "Genetics, Stoicheometry and Kinetics of Multiple Protein Assembly: the case for a Rotavirus Like Particle", funded by FCT (POCTI/BIO/55975/2004)
2005-2009 - "Epidemiology and new generation vaccines for Ehrlichia and Anaplasma infections of ruminants, EPIGENEVAC", funded by EU (FP6-003713-INCO-DEV-1)
2004-2006 - "Integrated strategy for the production, purification and storage of adenovirus", funded by FCT, Portugal (POCTI/BIO/46515/2002)
2003-2006 - "Metabolic Trafficking between neurons and astrocytes under stress conditions implicated in neurological disorders”, funded by FCT, Portugal (POCTI/BIO/39214/2001)
2003-2005 - “Integrated Strategies for efficient therapeutic retrovirus based on modular cell lines”, funded by the EU. (QLK3-CT-2002-01949)
2003-2005 - “Novel strategies for a safe rotavirus vaccine”, funded by the EU (QLRT-2001-01249)
2001-2004 - "Mass production of Cowdria ruminantium to produce a cost effective veterinary vaccine against heartwater", funded by the EU (8 ACP TPS 040)
2001-2004 - "Development of Oral Vaccines, Role of Wildlife in The Maintenance of these Diseases", funded by the EU (ICA4-CT-2000-30027)
2001-2003 - "Stabilization of retroviruses for gene therapy clinical applications", funded by FCT, Portugal (POCTI/BIO/35695/2000)
2001-2003 - "Cell cycle control for better biotechnological methods in therapeutic protein production", funded by FCT, Portugal (POCTI/BIO/35687/2000)
