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group leader ITQB, Av. República, 2781-901 Oeiras, Portugal |
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Microbial & Enzyme Technology
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INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA
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Our laboratory is interested in exploring the structure-function relationships of enzymes, with particular emphasis in prokaryotic laccases, that are the simplest members of the multicopper oxidase (MCO) family of enzymes that includes ascorbate oxidase (L-ascorbate oxygen oxidoreductase, EC 1.10.3.3) and human ceruloplasmin (Fe(II) oxygen oxidoreductase, EC 1.16.3.1). Laccases due to their high relative non-specific oxidation capacity, find an important role in diverse biotechnological applications. The aim is to understand the structural determinants of activity, specificity and stability by an integrated approach involving biochemical, biophysical and molecular biology approaches. Our final objective is to build industrial laccases taking advantage on the available protein engineering tools and modern analytical techniques. |
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Overview |
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Webmaster: André Fernandes |
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Design by: Lígia Martins & André Fernandes |
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Logo by: Lígia Martins |
