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Andreas Bohn Lab

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The core mission of the Systems Biodynamics Lab is the creation of systems-level knowledge in environmental life sciences and biotechnology by application of computational and mathematical tools for the simulation of dynamical processes and for data management and analysis.

 

 

andreas bohn

Andreas Bohn
Investigador Auxiliar
PhD in Physics (2003), Darmstadt University of Technology, Germany

Phone (+351) 214469852 | Extension 1852
abohn@itqb.unl.pt


Research Interests

The scientific interests of the Systems Biodynamics are rooted in the use of quantitative, computational tools to elucidate how multi-cellular systems and entire organisms respond to dynamical changes of their natural environment. With a focus on (sun-)light as principal driving force, typical studies involve the simulation and analysis of circadian rhyhms in plants and humans, or growth processes and population dynamics of phototrophic microbial biofilms.

Through close collaborations with the scientific community at ITQB-NOVA in recent years, this has been complemented with developing bioinformatics solutions for the study of molecular processes in plants, with a focus on transcriptomics studies of developmental processes and stress responses in economically relevant species such as cork oak, pine or coffee.

The methodology of the laboratory is based on a translational from-algorithms-to-insight approach: more than focusing on the development of new numerical methods, we attempt to find a suitable existing solution for a concrete biological problem in order to maximize the knowledge gain from a given experimental set-up. Feedback from the real-world experience may serve to accelerate the development of best practices in computational biology.

Group Members


Selected Publications

  1. Di Pippo F, Ellwood NTW, Guzzon A, Bohn A, Congestri R (2014).
Biomass accumulation and species succession in cultured phototrophic biofilms
Eur J Phycol 49: 384-394.

  2. Pereira-Leal JB, Abreu IA, Alabaça CS, Almeida MH, Almeida P et al.
(2014). A comprehensive assessment of the transcriptome of the cork oak (Quercus suber) through EST sequencing
    BMC Genomics 15: 371.

  3. Wey D, Bohn A, Menna-Barreto L (2012).
Daily rhythms of native Brazilians in Summer and Winter.
Physiol Behav 105: 613-620.

Laboratory's Website

For further information please visit the laboratory's website

 

Biodinâmica de Sistemas

O laboratório de Systems Biodynamics usa métodos quantitativos e computacionais para estudar a resposta de biosistemas multi-celulares e organismos inteiros a mudanças dinámicas no seu ambiente natural. Típicos projetos envolvem a simulação e análise de ritmos circadianos em plantas e animais, ou, também, o crescimento e a dinámica populacional de biofilmes microbianos fototróficos.

Nos últimos anos, em estreita colaboração com vários grupos de investigação do ITQB-NOVA, o Systems Biodynamics Lab começou a desenvolver soluções bioinformáticas para a investigação de processos moleculares em plantas, especialmente na transcritómica do desenvolvimento e a resposta ao estresse de plantas com alto valor económico, como o sobreiro, o pinheiro e o café.

Mais do que desenvolver novos métodos computacionais, a abordagem do Systems Biodynamics Lab consiste em achar os melhores métodos existentes para maximizar o ganho de conhecimento de cada arranjo experimental.

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