CurriculumVitae

Cláudio M. Soares

 (Simplified version)

20171127

 

1-Personal data

2-Academic degrees

3-Scientific interests

4-Positions

5-Administrative activities

6-Teaching activities

7-Financed research projects

8-Work as referee

9-Participation in evaluation of research and training projects

10- Organisation of meetings and courses

11-Publications in peer-reviewed journals

 

 

 

1-Personal data

Name: Cláudio Manuel Soares

 

Date of birth: 1966-08-24

 

Mail address:

Instituto de Tecnologia Química e Biológica

Universidade Nova de Lisboa

Av. da República

2780-157 Oeiras

Portugal

 

Telephone: +351 21 4469610

Fax: +351 21 441 1277

Email: claudio@itqb.unl.pt

WWW: http://www.itqb.unl.pt/~claudio

 

 

2-Academic degrees

 

- PhD in Biochemistry (theoretical/computational) - 1994 - Universidade de Lisboa, Portugal / Uppsala University, Sweden.                     

 

- Filosofie Licentiatexamen - 1994 - Department of Physical Chemistry, Uppsala University, Sweden. This Swedish degree is higher than a Master.

 

- Licenciatura in Biochemistry - 1989 -Department of Chemistry, Faculdade de Ciências da Universidade de Lisboa. Final classification of 17 (scale 0-20). This Portuguese degree is higher than a BSc.

 

 

3-Scientific interests

 

Main areas

Molecular modelling of biomolecules / Structural bioinformatics, Structural Biology, Biophysics, Bioenergetics.

 

Specialised areas

Redox proteins and processes, Electron and Proton transfer, Protein structure prediction, Enzyme catalysis, Proteins with biomedical interest, Software development for molecular modelling.

 

 

4-Positions (in reverse order)

 

- July 2014 to present day – Dean of the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa.

 

- January 2015 to the present day - Head of the Molecular, Structural and Cellular Microbiology – MOSTMICRO Research Unit of ITQB.

 

- March 2005 to present day – Associate Professor at the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa.

           

- February 1999 to present day - Leader of the Protein Modelling Laboratory at the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa.

Present research staff of the Protein Modelling Group:

                        -Ana Sofia Oliveira, Pos-Doc

                        -Diana Lousa, Pos-Doc

                        -João Damas, PhD student

                        -Davide Cruz, PhD student

                        -Barbara Abreu, PhD student

                        -Cesar Pimenta, PhD student

                        -Tiago Barbosa, Master student

                        -André Marques, Master student

                        -Tiago Resende, Co-supervised PhD student with Isabel Rocha, U. Minho

                        -Joana Azevedo Oliveira, Co-supervised PhD student with Isabel Rocha, U. Minho

                        -Francisco Fernandes, Co-supervised Pos-Doc with Alfredo Ferreira, IST, ULisboa

 

Former members include:

            -Carla Baltazar, former PhD student

            -Daniel Machado, Former Pos-Doc student, co-supervised with Isabel Rocha, U. Minho

-Selin Pars, former Erasmus student from Turkey

            -Andreia Rogério, Summer student from IST-UL

-Jorge Antunes, former Master Student

-Hélia Jeremias, former research student, now a research student in FCUL.

-Ana Carolina Leote, Summer student from IST-UL

            -Emanuel Lopes, Summer student from IST-UL

-Luis Demmelhuber, former Erasmus student from University of Applied Science Weihenstephan-Triesdorf, Germany.

-Rita Melo, former Post-Doc, now a Post-doc in ITN

-Carlos Fernández Rodríguez, former Erasmus student from Univ. of Leon, Spain.

            -Bruno Victor, Post-Doc, former Post-Doc, now working in BIOSIM2 in Cantanhede, Portugal.

-Maria Luísa Rodrigues, former Post-Doc (also affiliated with the Computational Genomics group, IGC, PT, headed by José Pereira Leal), now a teacher.

            -Joana Vaz, former research student, now a Master student in the UK.

            -Luis Pereira, former research student, now a research student at ITQB.

-Nuno Micaêlo, former PhD student, now Auxiliary researcher at Universidade do Minho

-Carlos A. Cunha,former Post-Doc, now working at DHL

-Zélia Ferreira, Research student, now a research student at Universidade do Porto.

-Vitor Hugo Teixeira, former PhD student, now a post-doc at Universidade do Algarve.

-Paulo J. Martel, PhD, Assistant Prof. at Universidade do Algarve

-António M. Baptista, PhD, former post-doc, now a group leader at ITQB-UNL

-Joaquim Mendes, former PhD student, now a group leader at the Max Planck Institute of Molecular Physiology, Dortmund, Germany

-Nuno Elias, BSc, former Diploma student, now a Wine Engineer

 

 

- Member of the Scientific Council of TAGUSPARK – Parque de Ciência e Tecnologia, Portugal. From May 2013 to the present day.

 

- Member of the FEBS (Federation of European Biochemical Societies) Advanced Courses Committee. From January 2015 to the present day.

 

- General Secretary of the General Assembly of the Portuguese Biophysical Society – November 2008 to the present day.

 

- President of the General Assembly of the Portuguese Biochemical Society – January 2017 to the present day.

 

- Member of European Science Foundation (ESF) College of Expert Reviewers – October 2016-October 2019

 

 

- Member of the Council of the International Union for Pure and Applied Biophysics (IUPAB). From November 2011 to July 2017.

 

- General Secretary of the General Assembly of the Portuguese Biochemical Society – January 2013 to December 2016.

 

- March 2013 to June 2014 – Interim Dean of the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa.

 

- March 2011 to March 2013 – Vice-Dean of the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa.

 

- May 2009 to Februry 2011 - Head of the Biological Chemistry Division, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa (mandate suspended in March 2010 when became Vice-Dean).

 

- December 2002 to October 2008 - Chairman of the Portuguese Biophysical Society.

 

- June 2005 to February 2008 – Vice-Dean of the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa.

 

- Member of the Scientific Advisory Council of the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa - 2003 until 2008.

 

- Member of the Co-ordinating Committee of the Scientific Council of the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa - 1999 until the end of 2002.

 

- February 1999 until February 2005 - Invited Assistant Professor at the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa.

 

- November 1998 to January 1999 - Research associated at the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa. Co-ordinator of the Protein Modelling Unit.

 

- November 1994 to October 1998 - Post-doc at the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, in the group of Prof. Maria A. Carrondo. During this time he was responsible for the co-ordination of the Protein Modelling Unit formed meanwhile.

 

- November 1990 to April 1993 - PhD student with a JNICT scholarship at the Department of Physical Chemistry, Uppsala University, Sweden, under the supervision of Professor Orlando Tapia.

 

- October 1988 to September 1989 - Diploma student at the Centro de Bioquímica e Fisiologia Animal do Instituto Rocha Cabral, Lisbon under the supervision of Prof. Ana Ponces Freire.

           

 

5-Administrative activities

 

Dean of the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa - July 2014 to present day.

 

Interim Dean of the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa - March 2013 to June 2014.

 

Vice-Dean of the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa -  March 2011 to March 2013.

 

Member of the Scientific Council of ITQB –From 2009 to February 2011 (mandate suspended in March 2010 when became Vice-Director).

 

Member of the Pedagogical Council of ITQB –From 2009 to February 2011 (mandate suspended in March 2010 when became Vice-Director).

 

Member of the Institute Council of ITQB –From 2009 to February 2011 (mandate suspended in March 2010 when became Vice-Director).

 

Vice-Director of the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa. From June 2005 to February 2008.

 

Chairman of the Portuguese Biophysical Society. From December 2002 to to October 2008.

 

Member of the directing board of the Portuguese Biophysical Society. From 1998 to the end of 2002. From November 2008 to the present day.

 

Member of the Co-ordinating Committee of the Scientific Council of the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa. From 1999 to February 2008.

 

Member of the organising committee of the Chemical and Biological Sciences PhD program of ITQB-UNL. From 2003 to 2006.

 

Deputy Director of the Gulbenkian PhD Program in Computational Biology. From 2007 to the present day.

 

 

6-Teaching activities

 

Supervision of Pos-Docs: Responsible for the supervision of 8 pos-doctoral fellows.

 

Supervision of PhD students: Responsible for 7 PhD students that have finished and 6 PhD students currently doing their research.

 

Supervision of Diploma students: Responsible for 5 Diploma students that have finished.

 

Supervision of Master (pos-Bologna) students: Responsible for 2 Master students that has finished and 2 students pursuing the degree.

 

Supervision of Research students: Responsible for 14 research students, 8 of which have become PhD students meanwhile.

 

Teaching activities in PhD programs: Biomolecular modelling techniques in several ITQB-UNL PhD program (in the years of 1999, 2003-2017). Biomolecular modelling techniques in the Gulbenkian PhD program in biology and medicine (in the years of 1997, 1998, 1999, 2000 and 2001). Molecular modelling methodologies in the Gulbenkian Program in Computational Biology: co-coordinator of the submodule MSS2: Structures (DNA, RNA and proteins), lasting for three continuous weeks – 2005, 2006 and 2008. Protein structure prediction methodologies in the Bioinformatics course of the International Postgraduate programme from Universidade do Minho – 2007. Molecular modelling methodologies in the MIT-Portugal Bioengineering PhD program. 2007-2017. Molecular modelling methodologies in the Gulbenkian Programme In Integrative Biomedical Sciences – PIBS. 2013-2014

 

Teaching activities in Master programs: Biomolecular modelling techniques in the Master degree in Biophysics of the University of Lisbon (in the year of 2002). Biomolecular modelling techniques in the Master degree in Biotechnology of the University of Algarve (in the year of 2002). Biomolecular modelling techniques in the Master degree in Molecular Genetics of the University of Minho (in the year of 2003). Biomolecular modelling techniques in the Master degree in Pharmaceutical Chemistry of the Pharmacy Faculty from Lisbon University (in the year of 2004). Biomolecular modelling techniques in the Master degree in Biomedical Inorganic Chemistry of the Science Faculty from Lisbon University (in the year of 2005, 2006, 2007, 2008 and 2010). Biomolecular modelling techniques in the Master degree of Molecular Genetics and Biomedicine of FCT-UNL (in the year of 2009). Biomolecular modelling techniques in the Master degree of Biological Engineering of IST-UTL (in the years of 2009-2016). Biomolecular modelling applications in the Master degree of Bioinformatics of FCUL (in 2012). Molecular mechanics/dynamics, Molecular Visualization and Protein Structure Prediction in the Master degree of Biomedical Sciences of Universidade do Algarve (in 2012 and 2014). Biomolecular modelling methodologies in the Biochemistry for Health UNL Master program (2017)

 

 

7-Financed research projects

 

i) Principal researcher in the PRAXIS XXI/JNICT (PBICT/BIO/2037/95) project “Molecular modelling of proteins involved in electron transfer processes”). January 1996 - December 1998.

 

ii) Responsible for the protein modelling activities in the JNICT Luso-Hungariun project “Crystal structure determination and molecular modelling of proteases and electron transfer proteins”.1996-1997.

 

iii) Responsible for the protein modelling activities in the PRAXIS XXI project “Structural determinants of electron transfer interactions between [Ni-Fe] hydrogenase and cytochrome c3 from D.desulfuricans ATCC 27774”. 1997-1998.

 

iv) Responsible for the protein modelling activities in the PRAXIS XXI project “Structural determination of proteins using X-ray crystallography and its structural implications".1997-1998.

 

v) Responsible for the protein modelling activities in the EC BIOTECNOLOGY PROGRAM AREA 6.1 project (BIO4-CT96-0413) “Construction of novel redox proteins from modular building blocks”. November 1996 - October 1999.

 

vi) Responsible for the protein modelling activities in the PRAXIS XXI project PRAXIS/P/BIO/14314/1998 “Structure function relationships of serine hydrolases in non-conventional media”. October 2000 - September 2002.

 

vii) Principal researcher in the FCT Sapiens project POCTI/BME/32789/99 entitled "Molecular modelling of key redox proteins in bacterium metabolism: methodology and applications". July 2001- June 2004.

 

viii) Responsible for the protein modelling activities in the FCT Sapiens project POCTI/BME/32789/99 entitled "Novel respiratory complexes: molecular basis for energy transduction". 2001-2003.

 

ix) Responsible for the protein modelling activities in the FCT Sapiens POCTI/QUI/43323/2001 project entitled "Electron transfer mechanisms and dynamics of a proton thruster: cytochrome c3". 2001-2004.

 

x) Responsible for the protein modelling activities in the FCT Sapiens POCTI/MGI/47382/2002 project entitled "Folding, processing and function of normal and mutant cystic fibrosis transmembranar conductance regulator: structural implications". 2002-2005.

 

xi) Involved in the FCT Sapiens POCTI/BME/45810/2002 project entitled “Increasing realism in protein modelling: including pH and redox effects into molecular dynamics simulations”. 2003-2006.

 

xii) Responsible for the protein modelling activities in the FCT Sapiens POCTI/BIO/57083/2004 project entitled “Nano-engineering of bacterial laccases”. 2005-2008.

 

xiii) Responsible for the protein modelling activities in the FCT Sapiens POCTI/BIO/57193/2004 project entitled “Rationalization of cutinase enantioselectivity in nonaqueous media”. 2005-2008

 

xiv) Responsible for the protein modelling activities at the ITQB-UNL partner of the EU FP6-2004-NMP-NI-4/02456 IP project. “White biotechnology for added value products from renewable plant polymers: Design of tailor-made biocatalysts and new industrial bioprocesses” (acronym BIORENEW).  2006-2010

 

xv) Responsible for the protein modelling activities in the FCT project PTDC/BIA-PRO/70429/2006. “Towards biohydrogen production – study of a high-activity, oxygen-resistant bacterial hydrogenase”. 2007-2010

 

xvi) Responsible for the protein modelling activities in the FCT project PTDC/BIA-PRO/XXXXX/2006. “Microbial enzymes involved in superoxide and nitric oxide reduction”. 2008-2010

 

xvii) Responsible for the protein modelling activities in the FCT project PTDC/BIO/73946/2006. “Site-specific labeling of proteins by a novel type of transglutaminase isolated from spores of Bacillus subtilis.”. 2009-2012

 

xviii) Responsible for the protein modelling activities in the FCT project PTDC/QUI/65640/2006 “Investigation of redox-state-specific protein-protein interactions and energy transduction in the electron transfer chains of sulfate reducing bacteria”. 2009-2011

 

xix) Responsible for the protein modelling activities in the MIT-Pt/BS-BB/0014/2008 project “Structural and functional study of the proteins mediating electron transfer between microorganisms and solid substrates with relevance for bio-energy production”. 2009-2012

 

xx) Responsible for the protein modelling activities in the FCT PTDC/AGR-AAM/102345/2008 project “Breaking Down The Wall - Microbial Hemicellulases for saccharification”. 2010-2012

 

xxi) Involved in the FCT project PTDC/QUI-BIQ/105238/2008 “Study of pH-dependent protein misfolding using state-of-the-art molecular modelling methods”. 2010-2012.

 

xxii) Involved in the FCT project PTDC/BIA-PRO/104378/2008 “Including protonation effects in the simulation of peptides and proteins in membrane environments”. 2010-2012

 

xxiii) Principal researcher in the FCT project PTDC/QUI-BIQ/113446/2009 entitled "Proton transfer and proton pumping in haem-copper oxidases. Methodological developments and their application to unravel the molecular mechanism ". 2010- 2014.

 

xxiv) Principal researcher in the FCT project PTDC/QUI-BIQ/114774/2009 entitled "Membrane fusion mechanism of Influenza Hemagglutinin: a simulation and biophysical approach." 2010- 2014.

 

xxv) Responsible for the protein modelling activities in the PTDC/QUI-BIQ/117799/2010 entitled “Interaction of proteins with CO releasing molecules (CORMS).” 2011-2014.

 

xxvi) Responsible for the protein modelling activities in the PTDC/BBB-BEP/0934/2012 entitled “Structural Determinants of Oxygen Tolerance in a NiFeSe Hydrogenase.” 2013-2014.

 

xxvii) Responsible for the protein modelling activities in the PTDC/BBB-BEP/2885/2014 entitled “Engineering a highly active NiFeSe Hydrogenase for electrocatalytic and photocatalytic applications.” 2016-2018.

 

xxviii) Principal researcher in the European PRACE Preparatory Access Proposal 2010PA3220 entitled “Probing the pH-induced conformational change of influenz hamaggglutinin using micro-second long simulations“.– 205.000 Core-hours. 2016

 

 

8-Work as referee and editor in scientific journals

 

As member of the Editorial Board

i) Biophysical Reviews – In the years of 2011-2017.

ii) PLOS One – In the years of 2012-2017.

iii) Scientific Reports – In the year of 2013-2017

 

As associate editor.

i) Journal of Biophysics – In the years of 2008-2018. Terminated.

ii) BioMed Research International (old Journal of Biomedicine and Biotechnology) – In the years of 2008-2017

 

 

As referee

i) Biopolymers - In the year of 1999.

ii) Proteins - In the years of 2000 and 2004.

iii) Biophysical Journal - In the years of 2002, 2006, 2010, 2011, 2015, 2016 and 2017.

iv) Journal of Biological Inorganic Chemistry- In the years of 2002, 2003, 2009 and 2013.

v) Protein Science - In the years of 2003, 2004 and 2010.

vi) Journal of Computational Chemistry - In the year of 2003.

vii) FEBS Letters – In the years of 2005, 2006, 2011, 2013, 2015.

viii) Journal of Cystic Fibrosis - In the year of 2004.

ix) Protein Engineering Design and Selection – In the years of 2005 and 2012.

x) Biophysics (Biophysical Society of Japan) – In the year of 2006

xi) Journal of Chemical Physics – In the years of 2006, 2008, 2013, 2015 and 2017

xii) Journal of Biotechnology – In the year of 2006

xiii) Journal of Physical Chemistry – In the years of 2006, 2007, 2008, 2010, 2011, 2014, 2015, 2016.

xiv) BMC Biotechnology – In the year of 2006

xv) Journal of Molecular Graphics and Modelling – In the years of 2006, 2009, 2012 and 2013.

xvi) Chemical Physics Letters – In the years of 2006, 2012, 2014

xvii) Extremophiles – In the years of 2007, 2008 and 2010

xviii) Journal of Computer-Aided Molecular Design – In the years of 2007 and 2010.

xix) Molecular Simulation – In the years of 2008 and 2013.

xx) Journal of Molecular Catalysis – In the years of 2008 and 2012.

xxi) Protein and Peptide Letters – In the years of 2008 and 2012.

xxii) FEBS Journal – In the year of 2008

xxiii) Journal of Peptide Science – In the year of 2007

xxiv) Process Biochemistry – In the year of 2009

xxv) International Journal of Molecular Sciences – In the year of 2010

xxvi) Langmuir – In the years of 2010 and 2016

xxvii) Journal of the American Chemical Society – In the years of 2010 and 2011.

xxix) Biotechnology and Bioengineering – In the years of 2011 and 2016

xxx) Journal of Chemical Information and Modeling – In the year of 2011.

xxxi) Theoretical Chemistry Accounts – In the year of 2012.

xxxi) Proc. Natl. Acad. Sci. USA – In the year of 2011.

xxxii) The Protein Journal – In the year of 2011.

xxxiii) Journal of Chemical Information and Modelling – In the year of 2011.

xxxiv) Bioresource Technology – In the year of 2011.

xxxv) PLOS One – In the years of 2011 and 2012.

xxxvi) Journal of Molecular Modelling – In the year of 2011.

xxxvii) ChemPhysChem – In the year of 2012.

xxxviii) FEMS Microbiology Letters – In the year of 2012.

xxxix) ACS Chemical Biology – In the year of 2012.

xxxx) International Journal of Biological Macromolecules – In the year of 2013

xxxxi) Advances in Biology – In the year of 2013

xxxxii) BBA-Biomembranes – In the year of 2014

xxxxiii) Biochemistry – In the years of 2014 and 2016

xxxxiv) Journal of Chemical Theory and Computation – In the years of 2014 and 2016

xxxxv) PLOS Computational Biology – In the year of 2014

xxxxvi) Journal of Physical Chemistry Letters – In the year of 2015

xxxxvii) Physical Chemistry Chemical Physics – In the year of 2015

xxxxviii) Enzyme and Microbial Technology – In the year of 2015

xxxxix) PeerJ – In the year of 2016

xxxxx) Molecular Physics – In the year of 2016

xxxxxi) International Journal of Molecular Sciences – In the year of 2017

 

 

 

9- Participation in evaluation of research and training projects, and prizes

 

i) Evaluation of Marie Curie Research Training Networks, both remotely as well as in Brussels, Belgium, during the FP6-2002-Mobility-1 call - end of February, beginning of March, 2004.

 

ii) Evaluation of FP6-NEST research projects, in the 2003 call, at the end of May 2004.

 

iii) Evaluation of Marie Curie Research Training Networks, both remotely as well as in Brussels, Belgium, during the FP6-2004-Mobility-1 call – end of February, beginning of March, 2005.

 

iv) Evaluation of Marie Curie fellowships, both remotely as well as in Brussels, Belgium, during the FP6-Mobility-5/6/7 LIF call – April and May, 2006.

 

v) Evaluation of projects PICT from the Agencia Nacional de Promoción Cientifíca y Tecnológicas (Argentina). 2007, 2008, 2010 and 2011.

 

vi) Evaluation of a project from the Grant Agency, Academy of Sciences of the Czech Republic. 2008.

 

vii) Evaluation of Marie Curie fellowships both remotely as well as in Brussels, Belgium, during the FP7-PEOPLE-IEF/IOF/IIF-2008 LIF call – October 2008.

 

viii) Evaluation of a project from the NWO Grant Agency of The Netherlands. 2009.

 

xix) Evaluation of Marie Curie fellowships, both remotely as well as in Brussels, Belgium, during the FP7-PEOPLE-2009-IEF-IIF-IOF LIF call – October, 2009.

 

xx) Speaker in the information session “Acções Marie Curie” held at ITQB where he presented a talk entitled “The experience of a Marie Curie Evaluator”. May 17th, 2010.

 

xxi) Evaluation of Marie Curie fellowships, both remotely as well as in Brussels, Belgium, during the FP7-PEOPLE-2010-IEF-IIF-IOF LIF call – October, 2010.

 

xxii) Evaluation of a project from the National Science Foundation, USA, 2011.

 

xxiii) Evaluation of Marie Curie Career Integration Grants, both remotely as well as in Brussels, Belgium, during the FP7-PEOPLE-2011-CIG call – April, 2011.

 

xxiv) Evaluation of a project from the Emmy Noether-Programm Nachwuchsgrupper Neuantrag of the German Research Foundation (Deutsche Forschungsgemeinschaft), Germany, 2011.

 

xxv) Evaluation of two projects for the Austrian Science Fund, Austria, 2011.

 

xxv) Evaluation of two research projects for the Cyprus Research Promotion Foundation, Cyprus, 2011.

 

xxvi) Evaluation of a research proposal from Agência de Inovação, Portugal. 2011.

 

xxvii) Evaluation of Marie Curie fellowships, both remotely as well as in Brussels, Belgium, during the FP7-PEOPLE-2011-IEF-IIF-IOF LIF call – October, 2011.

 

xxviii) Evaluation of Marie Curie Career Integration Grants, both remotely as well as in Brussels, Belgium, during the FP7-PEOPLE-2012-CIG call – April, 2012.

 

xxvix) Evaluation of two projects from the National Science Centre, Poland, 2012

 

xxx) Evaluation of National Fundação para a Ciência e Tecnologia PhD and Post-Doctoral fellowships in the Biological Sciences Panel – July 2012.

 

xxxi) Evaluation of a project from the American Chemical Society Petroleum Research Fund – July 2012.

 

xxxii) Evaluation of a project from the Romanian National Research Council – August 2012.

 

xxvii) Evaluation of Marie Curie fellowships, both remotely as well as in Brussels, Belgium, during the FP7-PEOPLE-2012-IEF-IIF-IOF LIF call – October, 2012.

 

xxxiii) Member of the jury of the Santander Totta – Universidade Nova de Lisboa award, 2012/2013 Edition – Exact Sciences and Engeneering. January-Februry 2013.

 

xxxiii) Speaker in the information session “FP7 / Marie Curie / Sessão de Informação Bolsas Individuais” held at Reitoria da Universidade de Lisboa where he presented a talk entitled “Evaluating Individual fellowships: an experience”. March 14th, 2013.

 

xxxiv) Evaluation of one project from the National Science Centre, Poland, 2013.

 

xxxv) Evaluation of one projects for the Austrian Science Fund, Austria, 2013.

 

xxxvi) Evaluation of FP7 ERA Chairs, both remotely as well as in Brussels, Belgium, during the– July, 2013.

 

xxxvii) Evaluation of Marie Curie fellowships, both remotely as well as in Brussels, Belgium, during the FP7-PEOPLE-2013-IEF-IIF-IOF LIF call – October, 2013.

 

xxxviii) Speaker in the information session “What’s in Horizon2020 for me?” held at Faculdade de Medicina da Universidade de Lisboa where he presented a talk entitled “Marie Skłodowska-Curie individual fellowships: a perspective from an evaluator’s side”. December 20th, 2013.

 

xxxix) Evaluation of Marie Curie fellowships, both remotely as well as in Brussels, Belgium, during the H2020-MSCA-IF-2015 call – November, 2015. During this period he has evaluated 23 proposals, being the rappourteur of 8.

 

xxxx) Evaluation of one project from the United States-Israel Binational Science Foundation, Israel, 2016.

 

xxxxi) Chair of the Experimental Biology and Biochemistry panel for the national evaluation of PhD and Post-Doctoral Fellowships from Fundação para a Ciência e Tecnologia (National Science Foundation, Portugal), 2016-2017

 

xxxxii) Evaluation of one project from the National Science Centre, Poland, 2016.

 

xxxxiii) Evaluation of two projects from the National Science Centre, Poland, 2017.

 

xxxxiv) Evaluation of one project from the Deutsche Forschungsgemeinschaft (German Research Foundation) on the Emmy Noether Programme, Germany, 2017.

 

xxxxv) Evaluation one individual proposal (36 months) from the Deutsche Forschungsgemeinschaft (German Research Foundation), Germany, 2017

 

 

11-Organisation of meetings and courses

 

i) Main organiser of the 2nd Short course of the Portuguese Biophysical Society "Simulation of biological processes. Practical approaches" – 2-3 of October 1999, Santarém, Portugal.

 

ii) In the organisation of the 3rd Short course of the Portuguese Biophysical Society "Proteins: from structure to dynamics" – 4-6 of October 2001, Santarém, Portugal.

 

iii) In the organisation of the 4th Short course of the Portuguese Biophysical Society "Bioenergetics: the cellular power plants" - 5-6 of October 2002, Santarém, Portugal.

 

iv) In the organisation of the 5th Short course of the Portuguese Biophysical Society "Genomics and Proteomics: biophysical perspectives". 17-19 of October 2003, Santarém, Portugal.

 

v) Main organiser of the 3rd Portuguese-Spanish Biophysics Congress. 29th October until November 1st 2004 in Lisbon, Portugal.

 

vi) In the organisation of the 6th Short course of the Portuguese Biophysical Society "From cellular transport to neurosciences: a biophysical perspective". 14-16 of October 2005, Santarém, Portugal.

 

vii) In the organisation of the 8th European Biological Chemistry Conference, EUROBIC 8. 2-6 of July, 2006, Aveiro, Portugal.

 

viii) In the organisation of the Oxizymes in Oeiras: 3rd European Meeting in Oxizymes, September 7-9, 2006, Oeiras, Portugal.

 

ix) In the organising and scientific committees of the VI Ibero-American Congress of Biophysics, September 24-27, 2006, Madrid, Spain.

 

x) In the organisation of the 7th Short course of the Portuguese Biophysical Society "Biospectroscopy and Imaging". 19-21 of October 2007, Santarém, Portugal.

 

xi) Main organiser of the 1st Portuguese-Spanish-British Joint Biophysics Congress 2008, 10-13th July, 2008, Lisbon, Portugal

 

xii) In the organisation of the Workshop “Structure, dynamics, and function of proteins”, 17-19 September, 2008, ITQB-UNL, Oeiras, Portugal

 

xiii) In the organisation of the 8th Short course of the Short course of the Portuguese Biophysical Society "Systems Biology". 30 October - 1 November 2009, Santarém, Portugal.

 

xiv) In the Scientific Committee of the IV Spanish-Portuguese Biophysical Congress. 7-10 July 2010, Zaragoza, Spain.

 

xv) In the Scientific Committee of the Xth Spanish Symposium on Bioinformatics (JBI2010), 27-29 October, Malaga, Spain.

 

xvi) In the organisation of the 9th Short course of the Short course of the Portuguese Biophysical Society "Protein folding, misfolding and disease". 8-10 October 2010, Santarém, Portugal.

 

xvii) In the Scientifc Committee of the Congresso Nacional de Bioquímica 2010, 15-17 December 2010, Porto, Portugal.

 

xviii) In the organisation of the 10th Short course of the Short course of the Portuguese Biophysical Society "Nanosciences for Life". 17-19 November 2011, Santarém, Portugal.

 

xix) In the organising committee of the “Jornadas de Bioinformática” 2012. 23-25 January 2012, Barcelona, Spain.

 

xxi) In the organisation of the EBSA (European Biophysical Societies' Association) 2013, Lisbon, Portugal

 

xxii) In the Scientific Committee of the XIX National Congress of Biochemistry, 8-10 December, 2016, Guimarães, Portugal.

 

xxiii) In the organisation of the 5th Iberian Biophysics Congress EBSA 15-17 June, 2016, Porto, Portugal

 

xxiv) In the National Organising Committee of the XXV National Meeting of the Portuguese Chemical Society, 16-19 of July of 2017, Lisbon, Portugal

 

xxv) In the Scientific Committee of the 19th IUPAB congress and 11th EBSA congress, Edinburgh,Scotland, UK, 16-20 July, 2017
10-Publications in ISI peer-reviewed journals

 

Co-author of 107 published or accepted papers in scientific journals. Co-author of 3 submitted manuscripts. Co-author of 2 papers in peer-reviewed book chapters. Co-author of 1 paper in a submitted peer-reviewed book chapter. Author of a review in a Portuguese publication.

 

ResearcherID: E-2675-2012

At 2017-11-27

Total number of accessible articles: 107

Total number of citations: 3494

Average citations per article: 32.65

h-index: 35

 

http://orcid.org/0000-0003-1154-556X

Scopus Author ID: 34973451500

 

 

 

1) Björkstén, J, Soares, CM, Nilsson, O, Tapia, O (1994) “On the stability and plastic properties of the interior L3 loop in R.capsulatus porin. A molecular dynamics study.” Protein Engineering, 7, 487-493

 

2) Soares, CM, Björkstén, J, Tapia, O (1995) “Perturbation-relaxation molecular dynamics simulations as a tool to explore conformational space. Reversible response of the L3 loop in porin towards charge screening effects”. Molecular Simulation, 15, 35-46

 

3) Soares, CM, Björkstén, J, Tapia, O (1995) “L3-loop mediated mechanisms of pore closing in porin. A molecular dynamics perturbation approach”. Protein Engineering, 8, 5-12

           

4) Frazão, C, Soares, CM, Carrondo, MA, Pohl, E, Dauter, Z, Wilson, KS, Hervás, M, Navarro, JA, De la Rosa, MA, Sheldrick, GM (1995) ”Ab initio determination of the crystal structure of cytochrome c6 from the green algae Monoraphidium braunii.”, Structure, 3, 1159-1169

 

5) Soares, CM, Martel, PJ, Carrondo, MA (1997) “Theoretical studies on the redox-Bohr effect in cytochrome c3 from  Desulfovibrio vulgaris Hildenborough”. JBIC, 2, 714-727

 

6) Soares, CM, Martel, PJ, Mendes, J, Carrondo, MA (1998) “Molecular dynamics simulation of cytochrome c3. Studying the reduction processes using free energy calculations”, Biophys.J., 74, 1708-1721

 

7) Fontes, N, Almeida, MC, Peres, C, Garcia, S, Grave, J, Aires-Barros, MR, Soares, CM, Cabral, JMS, Maycock, CD, Barreiros, S (1998) ”Cutinase activity and enantioselectivity in supercriticalfluids”, Ind.Eng.Chem.Res., 37, 3189-3194

 

8) Mendes, J, Soares, CM, Carrondo, MA (1999) “Improvement of side-chain modelling in proteins with the Self-Consistent Mean Field Theory method based on an analysis of the factors influencing prediction”, Biopolymers, 50, 111-131

 

9) Petukhov, M, Cregut, D, Soares, CM, Serrano, L (1999) “Local water bridges and protein conformational stability”, Prot.Sci., 8, 1982-1989

 

10) Martel, PJ, Soares, CM, Baptista, AM, Fuxreiter, M, Náray-Szabó, G, Louro, RO, Carrondo, MA (1999) “Comparative redox and pKa calculations on cytochrome c3 from several Desulfovibrio species using continuum electrostatic methods.”, JBIC, 4, 73-86

 

11) Baptista, AM, Martel, PJ, Soares, CM (1999) “Simulation of electron-proton coupling with a Monte Carlo method: application to cytochrome c3 using continuum electrostatics”, Biophys.J., 76, 2978-2998.

 

12) Cunha, CA, Romão, MJ, Sadeghi, SJ, Valetti, F, Gilardi, G, Soares, CM (1999) “Effects of protein-protein interactions on electron transfer: docking and electron transfer calculations for complexes between flavodoxin and c-type cytochromes”,JBIC, 4, 360-374

 

13) Mendes, J, Baptista, AM and Carrondo, MA, Soares, CM (1999) "Improved modelling of side-chains in proteins with rotamer-based methods: a flexible rotamer model.", Proteins, 37, 530-543.

 

14) Pereira, MM, Santana, M, Soares, CM, Mendes, J, Carita, JN, Saraste, M, Carrondo, MA, Teixeira, M (1999) “The caa3 terminal oxidase of the thermohalophilic bacterium Rhodothermus marinus”, BBA, 1413, 1-13.

 

15) Burke, DF, Deane, CM, Nagarajaram, HA, Campillo, N, Martin-Martinez, M, Mendes, J, Molina, F, Perry, J, Reddy, BVB, Soares, CM, Steward, RE, Williams, M, Carrondo, MA, Blundell, TL, Mizuguchi, K (1999) “An iterative structure-assisted approach to sequence alignment and comparative modelling”, Proteins, Suppl 3, 55-60

           

16) Matias, PM, Saraiva, LM, Soares, CM, Coelho, AV, LeGall, J, Carrondo, MA (1999) “Nine-haem cytochrome c from Desulfovibrio desulfuricans ATCC 27774: primary sequence determination, crystallographic refinement at 1.8Å and modelling studies of its interaction with the tetrahaem cytochrome c3 from the same organism”, JBIC, 4, 478-494

 

17) Frazão, C, Bento, I, Costa, J, Soares, CM, Veríssimo, P, Faro, C, Pires, E, Cooper, J, Carrondo, MA (1999) “Crystal structure of cardosin A, a glycosylated and Arg-Gly-Asp containing aspartic proteinase from the flowers of Cynaracardunculus L.”, J.Biol.Chem., 274, 27694-27701

 

18) Power, DM, Elias, NP, Richardson, SJ, Mendes, J, Soares, CM, Santos, CRA (2000) "Evolution of the Thyroid Hormone Binding Protein, Transthyretin", Gen. Comp. Endocrinol., 119, 241-255

 

19) Sadeghi, SJ, Valetti, F, Cunha, CA, Romão, MJ, Soares, CM, Gilardi, G (2000) "Ionic strength dependence of the non-physiological electron transfer between flavodoxin and cytochrome c553 from D.vulgaris.", JBIC, 5, 730-737

 

20) Matias, PM, Soares, CM, Saraiva, LM, Coelho, R, Morais, J, LeGall, J, Carrondo, MA (2001) "[NiFe] hydrogenase from Desulfovibrio desulfuricans ATCC 27774: primary sequence determination, crystallographic refinement at 1.8 Å and modelling studies of its interaction with the tetra-haem cytochrome c3", JBIC, 6, 63-81

 

21) Baptista, AM, Soares, CM (2001) "Some theoretical and computational aspects of the inclusion of proton isomerism in the protonation equilibrium of proteins", J.Phys.Chem.B, 105, 293-309

 

22) Santana, M, Pereira, MM, Elias, NP, Soares, CM, Teixeira, M (2001) " Gene cluster of Rhodothermus marinus high-potential iron-sulfur protein : oxygen oxidoreductase, a caa(3)-type oxidase belonging to the superfamily of heme-copper oxidases ", J.Bacteriology, 183, 687-699

 

23) Mendes, J, Nagarajaram, HA, Soares, CM, Blundell, TL, Carrondo, MA (2001) "Incorporing a knowledge-based bias into an energy-based side-chain modelling method: application to comparative modelling of protein structure", Biopolymers, 59, 72-86

 

24) Mendes, J, Baptista, AM, Carrondo, MA, Soares, CM (2001) "Implicit solvation in the Self-Consistent Mean Field Theory method: side-chain modelling and prediction of folding free energies of protein mutants", J.Comp.Aid.Mol.Des., 15, 721-740

 

25) Abreu, IA, Saraiva, LM, Soares, CM, Teixeira, M, Cabelli, DE (2001) "The mechanism of superoxide scavenging by Archaeoglobus fulgidus neelaredoxin", J.Biol.Chem., 276, 38995-39001

 

26) Louro, RO, Bento, I, Matias, PM, Catarino, T, Baptista, AM, Soares, CM, Carrondo, MA, Turner, DL, Xavier, AV (2001) " Conformational component in the coupled transfer of multiple electrons and protons in a monomeric tetrahaem cytochrome", J.Biol.Chem., 276, 44044-44051

 

27) Teixeira, VH, Soares, CM, Baptista, AM (2002) "Studies of the reduction and protonation behaviour of tetrahaem cytochromes using atomic detail", JBIC, 7, 200-216

 

28) Martins, LO, Soares, CM, Pereira, MM, Teixeira, M, Costa, T, Jones, GH, Henriques, AO (2002) "Molecular and biochemical characterization of a highly stable bacterial laccase which occurs as a structural component of the Bacillus subtilis endospore coat", J.Biol.Chem., 277, 18849-18859

 

29) Baptista, AM, Teixeira, VH, Soares, CM (2002) "Constant-pH molecular dynamics using stochastic titration", J.Chem.Phys., 117, 4184-4200

 

30) Soares, CM, Teixeira, VH, Baptista, AM (2003) "Protein structure and dynamics in nonaqueous solvents. Insights from molecular dynamics simulation studies", Biophys.J., 84, 1628-1641

           

31) Victor, BL Vicente, JB, Rodrigues, R, Oliveira, S, Rodrigues-Pousada, C, Frazão, C, Gomes, CM, Teixeira, M, Soares, CM (2003) "Docking and Electron Transfer Studies between Rubredoxin and Rubredoxin:Oxygen Oxidoreductase", JBIC, 8, 475-488

 

32) Bento, I, Teixeira, VH, Baptista, AM, Soares, CM, Matias, PM, Carrondo, MA (2003) "Redox-Bohr and other cooperativity effects in the nine heme cytochrome c from Desulfovibrio desulfuricans ATCC 27774: crystallographic and modeling studies", J.Biol.Chem., 278, 36455-36469

 

33) Price, NJ, Pinheiro, C, Soares, CM, Ashford, D, Brownleader, M, Ricardo, CP, Jackson, P (2003) "A biochemical and molecular characterisation of LEP1, an extensin peroxidase from lupin", J.Biol.Chem., 278, 41389-41399

 

34) Bento, I, Matias, PM, Baptista, AM, da Costa, PN, van Dongen, WMAM, Saraiva, LM, Schneider, TR, Soares, CM, Carrondo, MA (2004) "Molecular basis for redox-Bohr and cooperative effects in cytochrome c3 from Desulfovibrio desulfuricans ATCC 27774: crystallographic and modelling studies of oxidised and reduced high resolution structures at pH 7.6", Proteins, 54, 135-152

 

35) Vidinha, P, Harper, N, Micaelo, NM, Lourenço, N, Richter, M, Cabral, JMS, Afonso, C, Soares, CM, Barreiros, S (2004) "Effect of immobilization support, water activity and enzyme ionization state on cutinase activity and enantioselectivity in organic media", Biotech. Bioeng., 85, 442-449

 

36) Soares, CM, Baptista, AM, Pereira, MM, Teixeira, M. (2004) "Investigation of protonatable residues in Rhodothermus marinus caa3 haem-copper oxygen reductase. Comparison with Paracoccus denitrificans aa3 haem-copper oxygen reductase", JBIC, 9, 124-134

 

37) Teixeira, VH, Baptista, AM, Soares, CM (2004) “Modelling electron transfer thermodynamics in protein complexes: interaction between two cytochromes c3", Biophys.J., 86, 2773-2785

 

38) Serrano, M, Neves, A, Soares, CM, Moran, CP, Henriques, AO (2004) “Role of the anti-sigma factor SpoIIAB in the regulation of sG during Bacillus subtilis sporulation”, J.Bacteriology, 186, 4000-4013

 

39) Victor, BL, Baptista, AM, Soares, CM (2004) "Theoretical identification of proton channels in the Quinol Oxidase aa3 from Acidianus ambivalens", Biophys.J., 87, 4316-25.

 

40) Matias, PM, Pereira, IAC, Soares, CM, Carrondo, MA (2005) "Sulphate respiration from hydrogen in Desulfovibrio bacteria: a structural biology overview", Prog.Biophys.Mol.Biol., 89, 292-329.

 

41) Kirichenko, AV, Pfitzner, U, Ludwig, B, Soares, CM, Vygodina, TV, Konstantinov, AA (2005) “Cytochrome c oxidase as a calcium binding protein. Studies on the role of a conserved aspartate in helice XI-XII cytoplasmic loop in cation binding.”, Biochemistry, 44, 12391-12401.

 

42) Rivas, L, Soares, CM, Baptista, AM, Simaan, J, Di Paolo, R, Murgida, DH, Hildebrandt, P (2005) “Electric-field induced redox potential shifts of tetraheme cytochromes c3 immobilised on self-assembled monolayers studied by surface enhanced resonance Raman spectroscopy and simulation studies”, Biophys.J., 88, 4188-4199.

 

43) Micaelo, NM, Teixeira, VH, Baptista, AM, Soares, CM (2005) “Water dependent properties of cutinase in nonaqueous solvents. A computational study of enantioselectivity.”, Biophys.J., 89, 999-1008.

 

44) Teixeira, VH, Cunha, CA, Machuqueiro, M, Oliveira, ASF, Victor, BL, Soares, CM, Baptista, AM (2005) “On the use of different dielectric constants for intrinsic and pairwise term in Poisson-Boltzmann studies of protein ionisation equilibrium.”, J.Phys.Chem.B, 109, 14691-14706.

 

45) Oliveira, ASF, Teixeira, VH, Baptista, AM, Soares, CM (2005) “Reorganization and conformational changes in the reduction of tetrahaem cytochromes.”, Biophys. J., 89, 3919-3930.

 

46) Valente, FM, Oliveira, ASF, Gnadt, N, Xavier, AV, Teixeira, M, Soares, CM, Pereira, IAC (2005) “Hydrogenases in Desulfovibrio vulgaris Hildenborough: structural and physiologic characterisation of the membrane-bound [NiFeSe] hydrogenase”, JBIC, 10, 667-682.

 

47) Lopes, SDN, Soares, CM, Baptista, AM, Goormaghtigh, E, Costa Cabral, BJ, Castanho, MARB (2006) “Conformational and orientational guidance of the analgesic dipeptide kyotorphin induced by lipidic membranes: Putative correlation toward receptor docking”, J.Phys.Chem.B, 110, 3385-3394.

 

48) Franco, IS, Mota, LJ, Soares, CM, Sá-Nogueira, I (2006) “Funtional domains of the Bacillus subtilis transcription factor AraR and identification of amino acids important for nucleoprotein complex assembly and effector-binding”. J.Bact., 188, 3024-3036

 

49) Teixeira, VH, Baptista, AM, Soares, CM (2006) “Pathways of H2 towards the active site of [NiFE]-hydrogenase”, Biophys.J., 91, 2035-45.

 

50) Micaelo, NM, Baptista, AM, Soares, CM (2006) “Parameterization of 1-Butyl-3-Methylimidazolium Hexafluorophosphate/Nitrate Ionic Liquid for the GROMOS force field”, J.Phys.Chem.B, 110, 14444-14451.

 

51) Rocha, R, Leal, SS, Teixeira, VH, Regalla, M, Huber, H, Baptista, AM, Soares, CM, Gomes, CM (2006) "Natural domain design: enhanced thermal stability of a zinc-lacking ferredoxin isoform shows that a hydrophobic core efficiently replaces the structural metal site”, Biochemistry, 45, 10376-10384

 

52) Roxo-Rosa,M, Xu, Z, M, Schmidt, Neto, MF, Cai, Z, Soares, CM, D, Sheppard, DN, Amaral, MD (2006) “Revertant mutants G550E and 4RK rescue cystic fibrosis mutants in the first nucleotide-binding domain of CFTR by different mechanisms”, PNAS, 103, 17891-17896

 

53) Iley, J, Moreira, R, Martins, L, Guedes, RC, Soares, CM (2006) “The Bsmoc group as a novel scaffold for the design of irreversible inhibitors of cysteine proteases” Bioorg. Med. Chem. Lett., 16, 2738-2741

 

54) Araújo, R, Silva, C, O´Neill, A, Micaelo, N, Guebitz, G, Soares, CM, Casal, M, Cavaco-Paulo, A (2007) “Tailoring cutinase activity towards polyethylene terephthalate and polyamide 6.6 fibers”, J. Biotechnol., 128, 849-857.

 

55) Micaelo, N, Soares, CM (2007) “Modeling hydration mechanisms of enzymes in nonpolar and polar organic solvents”, FEBS J., 274, 2424-2436.

 

56) Fernandes, AT, Soares, CM, Pereira, MM, Huber, R, Grass, G, Martins, LO (2007) “A robust metallo-oxidase from the hyperthermophilic bacterium Aquifex aeolicus”, FEBS J., 274, 2683-2694.

 

57) Franco, I, Mota, LJ, Soares, CM, Sá-Nogueira, I (2007) “Probing key DNA contacts in AraR-mediated transcriptional repression of the Bacillus subtilis arabinose regulon”, Nucleic Acids Res., 35, 4755-4766

 

58) Broco, M, Soares, CM, Oliveira, S, Mayhew, SG, Rodrigues-Pousada, C (2007) “Molecular determinants for FMN-binding in Desulfovibrio gigas Flavoredoxin”, FEBS Lett., 581, 4397-4402

 

59) Gaspar, P, Neves, AR, Shearman, CA, Gasson, MJ, Baptista, AM, Turner, DL, Soares, CM, Santos, H (2007) "The lactate dehydrogenases encoded by the ldh and ldhB genes in Lactococcus lactis exhibit distinct regulation and catalytic properties: comparative modelling to probe the molecular basis.”, FEBS J. 274, 5924-5936

 

60) Teixeira, VH, Soares, CM, Baptista, AM (2008) “Proton Pathways in a [NiFe]-Hydrogenase: A Theoretical Study", Proteins, 70, 1010-1022

 

61) Rodrigues, JV, Victor, BL, Huber, H, Saraiva, LM, Soares, CM, Cabelli, DE, Teixeira, M (2008) “Superoxide reduction by Nanoarchaeum equitans neelaredoxin, a “natural mutant” lacking the ferric sixth ligand glutamate”, JBIC, 13, 219-228

 

62) Micaelo, NM, Victor, BL, Soares, CM (2008) “Protein thermal stabilization by charged compatible solutes. Computational studies in rubredoxin from Desulfovibrio gigas”, Proteins, 72, 580-588

 

63) Micaelo, NM, Soares, CM (2008) “Protein structure and dynamics in ionic liquids. Insights from molecular dynamics simulation studies”. J.Phys.Chem.B, 112, 2566-2572

 

64) Durão, P, Chen, Z, Silva, CS, Soares, CM, Pereira, MM, Todorovic, S, Hildebrandt, P, Bento, I, Lindley, PF, Martins, LO (2008) “Proximal mutations at the type 1 copper site of CotA-laccase; spectroscopic, redox, kinetic and structural characterization of Ile494A and L386A mutants”., Biochemical J. 412, 339-346

 

65) Escrevente, C, Morais, VA, Keller, S, Soares, CM, Altevogt, P, Costa, J (2008) “Functional role of N-glycosylation from ADAM10 in processing, activity, stability and localization of the enzyme”, BBA, 1780, 905-913

 

66) Fonseca, BM, Saraiva, IH, Paquete, CM, Soares, CM, Pacheco, I, Salgueiro, CA, Louro, RO (2009) “The tetrahaem cytochrome from Shewanella oneidensis MR-1 shows thermodynamic bias for functional specificity of the different haems”, JBIC, 14, 375-385

 

67) Victor, BL, Baptista, AM, Soares, CM (2009) “Dioxygen and nitric oxide pathways and affinity to the catalytic site of ROO from Desulfovibrio gigas”, JBIC, 14, 853-862

 

68) Gonçalves, S, Borges, N, Esteves, AM, Victor, B, Soares, CM, Santos, H,  Matias, PM (2010) “Structural Analysis of Thermus thermophilus HB27 Mannosyl-3-phosphoglycerate Synthase Provides Evidence for a Second Catalytic Metal Ion and New Insight into the Retaining Mechanism of Glycosyltransferases “, J Biol Chem, 285, 17857-17868

 

69) Oliveira, ASF, Baptista, AM, Soares, CM (2010) “Insights into the ATP-hydrolysis mechanism of an ABC-transporter: conformational changes in the NBD dimer of MJ0796”, J Phys Chem B, 114, 5486-5496

 

70) Fernandes, AT, Damas, JM, Todorovic, S, Huber, R, Pogni, R, Soares, CM, Martins, LO (2010) “The Multicopper Oxidase from the Archaeon Pyrobaculum aerophilum Shows Nitrous Oxide Reductase Activity”, FEBS J., 277, 3176-3189

 

71) Bento, I, Silva, C, Chen, Z, Martins, LO, Lindley, PF, Soares, CM (2010) “Mechanisms underlying dioxygen reduction in laccases. Structural and modelling studies.”, BMC Struct. Biol. 2010, 10:28.

 

72) Machuqueiro, M, Campos, SRR, Soares, CM, Baptista, AM (2010) “Membrane-induced conformational changes of kyotorphin revealed by molecular dynamics simulations”, J Phys Chem B, 114, 11659–11667

 

73) Lousa, D, Baptista, AM, Soares, CM (2011) “Structural determinants of ligand imprinting: a molecular dynamics simulation study of subtilisin in aqueous and apolar solvents”, Prot.Sci., 20, 379-86.

 

74) Baltazar, C, Marques, MC, Soares, CM, DeLacey, AM, Pereira, IAC, Matias, PM (2011) “Nickel-Iron-Selenium Hydrogenases - An Overview”, Eur.J.Inor.Chem., 2011, 948-962.

 

75) Oliveira, ASF, Baptista, AM, Soares, CM (2011) “Conformational changes induced by ATP-hydrolysis in an ABC transporter: a molecular dynamics study of the Sav1866 exporter”, Proteins, 79, 1977-1990

 

76) Damas, JM, Oliveira, ASF, Baptista, AM, Soares, CM (2011) “Structural consequences of ATP hydrolysis on the ABC transporter NBD dimer: molecular dynamics studies of HlyB”, Prot.Sci., 20, 1220-1230

 

77) Varanda, C, Felix, MR, Soares, CM, Oliveira, S, Clara, MI (2011) “Specific amino acids of Olive mild mosaic virus coat protein are involved on transmission by Olpidium brassicae”, J. Gen.Virol., 92, 2209-2213

 

78) Oliveira, ASF, Baptista, AM, Soares, CM (2011) “Inter-domain communication mechanisms in an ABC importer: a molecular dynamics study of the MalFGK2E complex”, PLoS Comp.Biol., 7(8), e1002128

 

79) Soares, CM, Baptista, AM (2012) “Simulation of multihaem cytochromes”, FEBS Lett., 586, 510-518 (joint corresponding author).

 

80) Silva, CS, Damas, JM, Chen, Z., Brissos, V, Martins, LO, Soares, CM, Lindley, PF, Bento, I (2012) “The role of Asp116 in the reductive cleavage of dioxygen to water in CotA laccase: assistance during the proton transfer mechanism”, Acta Crys D, D68,186-193. (joint corresponding author).

 

81) Azoia, NG, Fernandes, MM, Micaelo, NM, Soares, CM, Cavaco-Paulo, A (2012) “Molecular modeling of hair keratin/peptide complex: using MM-PBSA calculations to describe experimental binding results”, Proteins, 80, 1409-1417

 

82) Baltazar, CSA, Teixeira, VH, Soares, CM (2012) “Structural features of [NiFeSe] and [NiFe] hydrogenases determining their different properties: a computational approach”, JBIC, 17, 543-555

 

83) Lousa, D, Baptista, AM, Soares, CM (2012) “Analyzing the molecular basis of enzyme stability in ethanol/water mixtures using molecular dynamics simulations”, J.Chem.Infor.Model., 52: 465-473

 

84) Lousa, D, Cianci, M, Helliwell, JR, Halling, PJ, Baptista, AM, Soares, CM (2012) “Interaction of counterions with subtilisin in acetonitrile: Insights from molecular dynamics simulations”, J.Phys.Chem.B, 116, 5838–5848

 

85) Campos, E, Asandei, A, McVey, CE, Dias, JC, Oliveira, ASF, Soares, CM, Luchian, T, and Astier, Y (2012) “The Role of Lys147 in the Interaction between MPSA-Gold Nanoparticles and the α-Hemolysin Nanopore”, Langmuir, accepted

 

86) Pires, S, Sezer, M, Soares, CM, Hemmingsen, L, Iranzo, O (2012) “Design of a peptidic turn with high affinity for Hg(II)”, Inorg.Chem., 51, 11339–11348.

 

87) Victor, BL, Baptista, AM, Soares, CM (2012) “Structural determinants for the membrane insertion of the transmembrane peptide of hemagglutinin from Influenza virus”, J.Chem. Infor. Model., 52, 3001–3012

 

88) Fonseca, BM, Paquete, CM, Neto, SE, Pacheco, I, Soares, CM, Louro, RO (2013) “Mind the gap: cytochrome interactions reveal electron pathways across the periplasm of Shewanella oneidensis MR-1”, Biochem. J., 449, 101-8.

 

89) Gutiérrez-Sanz, O, Marques, MC, Baltazar, CSA, Fernández, VM, Soares, CM, Pereira, IAC, De Lacey, AL (2013) “The cage effect in the catalytic activity of [NiFeSe] hydrogenases”, JBIC, 18, 419-427

 

90) Volkers, G, Damas, JM, Palm, GJ, Panjikar, S, Soares, CM, Hinrichs, W (2013) “Putative dioxygen binding sites and recognition of tigecycline and minocycline in the tetracycline-degrading monooxygenase TetX”, Acta Crys, D69, 1758-1767.

 

91) Lousa, D, Baptista, AM, Soares, CM (2013) “A molecular perspective on nonaqueous biocatalysis: Contributions from simulation studies” Phys.Chem.Chem.Phys., 15, 13723-13736

 

91) Lousa, D, Baptista, AM, Soares, CM (2013) “A molecular perspective on nonaqueous biocatalysis: Contributions from simulation studies” Phys.Chem.Chem.Phys., 15, 13723-13736

 

92) Damas, JM, Filipe, LCS, Campos, SRR, Lousa, D, Victor, BL, Baptista, AM, Soares, CM (2013) “Predicting the thermodynamics and kinetics of helix formation in a cyclic peptide model”, J.Chem.Theor.Comp., 9, 5148-5157

 

93) McVey, CE, Ferreira, MJ, Correia, B, Lahiri, S, de Sanctis, D, Carrondo, MA, Lindley, PF, de-Sá-Nogueira, I, Soares, CM, Bento, I (2014) “The importance of the Abn2 calcium cluster in the endo-1,5-arabinanase activity from Bacillus subtilis”, JBIC, 19, 505-513. (joint corresponding author)

 

94) Damas, JM, Baptista, AM, Soares, CM (2014) “A New Pathway for O2 Diffusion inside CotA Laccase and Implications on the Multicopper Oxidases Family”, JCTC, 10, 3525–3531

 

95) Paquete, CM, Fonseca, BM, Cruz, DR, Pereira, T, Pacheco, I, Soares, CM, Louro, RO (2014) Molecular mechanisms of electron shuttling across the microbe/metal space: Exploring the final frontier”, Frontiers in Microbiology, 5, 318.

 

96) Oliveira, ASF, Damas, JM, Baptista, AM, Soares, CM (2014) “Exploring O2 diffusion in A-type Cytochrome c Oxidases: molecular dynamics simulations uncover two alternative channels towards the binuclear site, PLoS Comp.Biol., 10, e1004010

 

97) Nobre, LS, Lousa, D, Pacheco, I, Soares, CM, Teixeira, M, Saraiva, LM (2015) “Insights into the structure of the diiron site of RIC from Escherichia coli”, FEBS Lett., 589, 426-433

 

98) Victor, BL, Lousa, D, Antunes, J, Soares, CM (2015) “Self-assembly molecular dynamics simulations shed light into the interaction of the influenza fusion peptide with a membrane bilayer”, J.Chem. Infor. Model., 55, 795–805

 

99) Alves, MN, Neto, SE, Alves, AS, Carrêlo, A, Pacheco, I, Fonseca, BM, Paquete, CM, Soares, CM, Louro, RO (2015) “Characterization of the periplasmic redox network that sustains the versatile anaerobic metabolism of Shewanella oneidensis MR-1”, Frontiers in Microbiology, 6, 665

 

100) Fernandes, CG, Plácido, D, Lousa, D, Brito, JAA, Isidro, A, Soares, CM, Pohl, J, Carrondo, MA, Archer, M, Henriques, AO (2015) “Structural and functional characterization of an ancient bacterial transglutaminase sheds light into the minimal requirements for protein cross-linking”, Biochemistry, 54, 5723-5734

 

101) Oliveira, ASF, Campos, SRR, Baptista, AM, Soares, CM (2016) “Coupling between protonation and conformation in cytochrome c oxidase: Insights from Constant-pH MD simulations”, BBA Bioenergetics, 1857, 759-771.

 

102) Lousa, D, Pinto, ART, Victor, BL, Laio, A, Veiga, AS, Castanho, MARB, Soares, CM (2016) “Fusing simulation and experiment: The effect of mutations on the structure and activity of the influenza fusion peptide”, Sci.Rep., 6, 28099.

 

103) Romão, CV, Vicente, JB, Borges, PT, Victor, BL, Lamosa, P, Silva, E, Pereira, L, Bandeiras, TM, Soares, CM, Carrondo, MA, Turner, D, Teixeira, M, Frazão, C. (2016) “Structure of Escherichia coli Flavodiiron nitric oxide reductase”, J.Mol.Biol., 48, 4686-4707

 

104) Marreiros, BC, Sena, FV, Sousa, FM, Oliveira, ASF, Soares, CM, Batista, AP, Pereira, MM (2017) “Structural and Functional insights into the catalytic mechanism of Type II NADH:quinone oxidoreductases family”, Sci.Rep., 7, 42303

 

105) Magalhães, PR, Oliveira, ASF, Campos, SRR, Soares, CM, Baptista, AM. (2017) “Effect of a pH gradient on the protonation states of cytochrome c oxidase: a CE/MC study”, JCIM, 57, 256-266.

 

106) Pereira, L, Saraiva, IH, Oliveira, AS, Soares, CM, Louro, RO, Frazão, C. (2017) “Molecular structure of FoxE, the putative iron oxidase of Rhodopseudomonas ferrooxidans SW2”, BBA Bioenergetics, 1858, 847-853

 

107) Sousa, FM, Sena, FV, Batista, AP, Athayde, D, Brito, JA, Archer, M, Oliveira, ASF, Soares, CM, Catarino, T, Pereira, MM (2017) “The key role of glutamate 172 in the mechanism of type II NADH:quinone oxidoreductase of Staphylococcus aureus”, BBA Bioenergetics, 1858, 823-832

 

108) Almadanim, MC, Gonçalves, NM, Rosa, MTG, Alexandre, BM, Cordeiro, AM, Rodrigues, M, Saibo, NJM, Soares, CM, Romão, CV, Oliveira, MM, Abreu, IA (2017) “The rice cold-responsive calcium-dependent protein kinase OsCPK17 is regulated by alternative splicing and post-translational modifications”, BBA Molecular Cell Research, accepted.