Our research is aimed at understanding the basic principles underlying the process of protein folding, a fundamental question in biology with implications in human disease. |
Protein misfolding and human disease Metal ions and protein folding Protein Stability |
Protein misfolding in fatty acid disorders 
Keywords: beta oxidation, MADD, ETF, ETF:QO; riboflavin; pharmacological chaperones
Frataxin folding, structure and function
Keywords: Freidreich's ataxia; neurodegeneration; iron; mitochondria
S100 proteins: amyloidogenesis, stability and metal ions
Keywords: Cancer; Inflamation; metals (Calcium, Zinc, Copper); amyloid; Alzheimer's Disease
Toxic aggregation of Superoxide Dismutase 1 and ALS
Keywords: Freidreich's ataxia; neurodegeneration; iron; mitochondria
Metalloprotein Folding and stability
Keywords: Ferredoxin; iron sulfur clusters; zinc; molten globule; heme proteins; spectroscopy
Protein stability: thermophilic proteins and proteomes
Keywords: Ferredoxin; iron sulfur clusters; zinc; molten globule; heme proteins; spectroscopy