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Participating Labs

 

The available laboratories for the 2022 Edition of Summer Science @ ITQB NOVA are:

 

Biology

1 - Human Microbiota - Xenobiotics Interactions 

We investigate the effects of metals (and other xenobiotics) in the gut microbiota composition and function and its effects on the host. We combine systems-based approaches and tailored molecular and biochemical experiments.
Responsible investigator: Sarela Garcia-Santamarina

 

2 - Intracellular Microbial Infection Biology 

In the IMIB laboratory we are interested in understanding the dynamics of the interaction between mammalian host cells and facultative intracellular bacterial pathogens using a combination of advanced microscopy approaches, organ-on-a-chip 3D cell system and classical cell biology and biochemistry approaches.
Responsible investigator: Pedro Matos Pereira

 

3 - Bacterial Cell Biology

In the Bacterial Cell Biology laboratory we use the Gram positive pathogen Staphylococcus aureus to study the mechanisms of cell division and of antibiotic resistance to cell wall targeting antibiotics
Responsible investigator: Mariana Pinho

 

4 - Control of Gene Expression 

Our studies focus on the control of gene expression. We have studied RNA degradation and characterised enzymes that mediate decay. Other interests are stress and microbial growth. This work has many applications in Biotechnology and Health.
Responsible investigator: Cecilia Arraiano

 

Biological Chemistry

5 - Protein Modelling

Computational Biology Lab devoted to protein simulation and protein design. Redox proteins, ABC transporters, viral membrane fusion proteins and enzyme engineering are some examples from the work we develop.
Responsible investigator: Cláudio Soares

6 - Bacterial Energy Metabolism Lab 

We study metabolic pathways and enzymes used for energy production in anaerobic microorganisms that are relevant for health and the environment, and explore their biotechnological applications.
Responsible investigator: Inês Cardoso Pereira

7- Membrane Protein Crystallography 

The student(s) coming to the MPX Lab will be included in a "from gene to structure approach", having the possibility of doing gene expression, protein purification, biophysical characterisation ("thermofluor and/or nanoDSF), and crystallisation. If time permits, the Student(s) will have access to state-of-the-art visualisation equipment working in stereo 3D to build the atomic model of the protein of interest. In summary: a shore choice for your internship at ITQB NOVA!
Responsible investigator: Margarida Archer

8 - Raman BioSpectroscopy Lab 

We are interested in fundamental questions and biotechnological applications of metalloproteins that carry out catalysis, detoxification, signaling, electron transfer and DNA repair. We study their mechanistic properties and immobilize them on tailored plasmonic metal hybrids to probe molecular processes at interfaces or construct biosensing devices. We use advanced vibrational spectroscopy, electrochemistry and spectroelectrochemistry as the main tools in our research.
Responsible investigator: Smilja Todorovic

 

9 - Dynamic structural biology Lab 

Our goal is to illuminate Biology with structure and dynamic details while studying how proteins fulfill their function. Fueled by Biochemistry, Biophysics and Structure, we pursue this goal while studying protein interactions and flexible macromolecules like intrinsically disordered proteins (IDPs) and relevant enzymes.
Responsible investigator: Tiago N. Cordeiro

 

10 - Multiscale Modeling Lab 

The Multiscale Modeling Lab focuses on the molecular-level details of biomolecular interactions. To this end we employ coarse-grained, atomistic, and hybrid MD simulations. Simulation and analysis software is also developed at the lab, with emphasis on large-scale parallelization.
Responsible investigator: Manuel N. Melo


Plant Sciences

11 - iPlantMicro

We aim to decipher plant-microbe beneficial interactions by using new-generation approach and a coherent perspective.
Responsible investigator: Juan Ignacio Vilchez

 

12 - Plant Functional Genomics 

We are following a genomics approach to explain plant stress responses, from the regulation of chromatin structure and transcriptional regulation to the study of post-translational protein modifications. We are also exploring and developing bioinformatics tools to study the stress response transcriptome.
Responsible investigator: Margarida Oliveira

 

13 - Proteome Regulation in Plants 

At the Proteome Regulation in Plants Laboratory we study the effects of post-translational modifications on protein function. Our working hypothesis is that the plant proteome can be induced to rapidly and efficiently deal with environmental changes, by manipulating its global regulation by post-translational modifications.
Responsible investigator: Isabel Abreu

 

14 - PlantX Lab

At the PlantX Lab we unveil the genetic and genomic basis of plant complex traits, such as nutritional or organoleptic quality or biotic/abiotic stress resistance, using different statistical genetic and genomic approaches.
Responsible investigator: Carlota Vaz Patto

 

 

         Chemistry

15 - Bioorganometallic Chemistry

Research in our group is centred in the synthesis of biologically relevant N-heterocyclic carbenes (NHCs), and on their applications as ligands to stabilize metallodrugs and catalysts. N-heterocyclic carbenes are extremely versatile ligands, as their electronic and steric characteristics can be easily modulated, reason for which they are widely explored in catalysis.
Responsible investigator: Ana Petronilho

 

16 - Bioorganic Chemistry  

Bioorganic Chemistry is the interface of organic chemistry and biology. Our research uses the principles and techniques of organic chemistry in attempting to solve problems of relevance to biology. We can design synthetic derivatives of natural products, that improve on nature.
Responsible investigator: Rita Ventura

 

         Science Communication office

The Science Communication team is involved in a number of activities ranging from Institutional Communication to Science Outreach activities, including Training in Science Communication for Researchers and promoting Media relations, to take the most recent scientific research closer to the community. 
Responsible person: Renata Ramalho

 

 

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