Research Projects 2010/11

Master Research Projects 2010/2011

Below you can find a list of Master Research Projects and Research Laboratories available to receive students in 2010/2011.

For applications and further informations, students should contact directly the Laboratory coordinators (please follow the laboratory links for contacts).  When available, the summaries of the research projects are also provided here.

Chemistry Divison

• Peptide-based duas probes for targeted molecular imaging of tumor angiogenesis [pdf.]
  Bioinorganic Chemistry and Peptide Design Laboratory - Olga Iranzo 
• Peptidomimetics for phosphoproteome analysis [pdf.]
  Bioinorganic Chemistry and Peptide DesignLaboratory - Olga Iranzo

• Enantioselective Organocatalysis: Synthesis and Application of Novel Organocatalysts [pdf.]  [pt]
  Bioorganic Chemistry Laboratory - Rita Ventura

• Synthesis of compatible solutes with protein thermostabilisation properties [pdf.] [pt] 
  Bioorganic Chemistry Laboratory - Rita Ventura

• Synthesis of DPD and new analogues, the precursor of AI-2, the bacterial signalling molecule for inter-species communication [pdf.]
  Bioorganic Chemistry Laboratory - Rita Ventura

• Sustainable catalysis based on N-heterocyclic carbene metal complexes [pdf.] [pt]
  Homogeneous Catalysis Laboratory - Beatriz Royo

• Synthetic and Mechanistic Studies on Metal Carbonyls for therapeutic delivery of CO [pdf.]
  Organometallic Chemistry Laboratory - Carlos C. Romão

• Metal Activation of CO for Energy Production [pdf.]
  Organometallic Chemistry Laboratory - Carlos C. Romão

• Fluorescent Nanoparticles for probing biological systems [pdf.]
  Organic Synthesis - Chris Maycock

• Desenvolvimento de quelantes macrocíclicos para complexação de iões metálicos de transição e lantanídeos com interesse em aplicações médicas [pdf.]
  Coordination and Supramolecular Chemistry - Rita Delgado 
• Reconhecimento molecular de aminoácidos por receptores macrobiciclicos heteroditópicos [pdf.]
  Coordination and Supramolecular Chemistry - Rita Delgado

Biological Chemistry Divison

• Energy Transduction by Complex I from Respiratory Chains [pdf.]
  Biological Energy Transduction Laboratory - Manuela M. Pereira

• Structural and functional investigation of type II NADH:quinone oxidoreductases [pdf.]
  Biological Energy Transduction Laboratory - Manuela M. Pereira

• Functional characterization of haem-copper oxygen reductases [pdf.]
  Metalloproteins and Bioenergetics Laboratory - Miguel S. Teixeira, Manuela M. Pereira

• Genomics and Stress Laboratory  - Claudina Rodrigues-Pousada

• Bactérias que produzem electricidade: Estudos de estrutura e função de proteínas envolvidas neste processo [pdf.]
  Inorganic Biochemistry and NMR Laboratory - Ricardo O. Louro

• Macromolecular Crystallography Unit [pdf.] - Maria Arménia Carrondo

• Structural studies on Superoxide reductases [pdf.]
  Macromolecular Crystallography Unit - Célia V. Romão, Tiago Bandeiras and Pedro Matias

• Aspectos Moleculares da Neurodegeneração a Esclerose Lateral Amiotrófica: efeito de mutações e factores celulares na formação de amiloíde da proteína SOD1 [pdf.]
  Protein Biochemistry, Folding & Stability Laboratory - Cláudio M. Gomes       position filled
• Modelação molecular/Bioinformática estrutural da hemaglutinina do vírus influenza [pdf.] 
  Protein Modelling - Cláudio M. Soares
• Modelação molecular/Bioinformática estrutural de ABC transporters [pdf.] 
  Protein Modelling - Cláudio M. Soares
• Analysis of protein‐ligand interactions by NMR spectroscopy [pdf.]
  Molecular Interactions and NMR - Patrick Groves
• New methods for the analysis of protein‐ligand interactions by NMR spectroscopy [pdf.]
  Molecular Interactions and NMR - Patrick Groves
• Determining the pH structural switch in calbindin D28k [pdf.]
  Molecular Interactions and NMR - Patrick Groves
• Characterization of a new EF-hand protein from Medicago truncatula[pdf.]
  Molecular Interactions and NMR - Patrick Groves
• Yeast two-hybrid at low pH [pdf.]
  Molecular Interactions and NMR - Patrick Groves
• Biological hydrogen production by anaerobic bacteria [pdf.]
  Bacterial Energy Metabolism - Inês Cardoso Pereira
• New Enzymes for Biotechnological Applications [pdf.]
  Microbial & Enzyme Technology - Lígia O. Martins
• Structural and Biochemical characterization of novel Fe 2+ metabolic pathways [pdf.]
  Biomolecular NMR - Manolis Matzapetakis
• Structural proteomics of thermostable protein libraries by NMR [pdf.]
  Biomolecular NMR - Manolis Matzapetakis
   

Biology Divison

• Single cell studies of the action of antibiotics [pdf.]
  Bacterial Cell Biology Laboratory - Mariana Gomes de Pinho
• Papel da cápsula de streptococcus pneumoniae no reconhecimento do peptidoglicano pelo sistema imunitário inato do hospedeiro [pdf.]

  Bacterial Cell Surfaces and Pathogenesis Laboratory - Sergio R. Filipe 

• Cell Signaling in Drosophila Project [pdf.]
  Cell Signaling in Drosophila Laboratory - Pedro Domingos 
• Glycobiology Laboratory Project [pdf.]
  Glycobiology Laboratory - Júlia Costa 

Plant Sciences Divison

• Chromosome cohesion and DNA double strand break damage repair [pdf.]
  Disease and Stress Biology Laboratory - José C. Nunes 

• Molecular Analysis of Class III HD-Zip transcription factors and role in plant vascular development [pdf.]
  Forest Biotechnology Laboratory - Célia Miguel

• Functional studies of genes involved in maritime pine embryogenesis [pdf.]
  Forest Biotechnology Laboratory - Célia Miguel

• Small RNAs in Quercus suber cork tissue [pdf.]
  Forest Biotechnology Laboratory - Célia Miguel

• Produção de proteínas recombinantes em culturas de células vegetais [pdf.]
  Plant Cell Biology Laboratory - Rita Abranches

• Caracterização citológica da ferrugem alaranjada do cafeeiro [pdf.]
  Plant Cell Biology Laboratory - Rita Abranches e Pedro Talhinhas

• Identification and functional characterization of rice transcription factors that regulate photosynthesis-related genes under salt stress [pdf.]
  Plant Genetic Engineering Laboratory - Nelson Saibo

• Análise proteómica do efeito de agentes antioxidantes num modelo celular de neurodegeneração [pdf.]
  Disease and Stress Biology laboratory - Cláudia Nunes dos Santos e Marta Alves

• Implementação do modelo celular de Parkinson em células SK-N-MC por exposição crónica à rotenona. Estudo do efeito de antioxidantes naturais [pdf.]
  Disease and Stress Biology laboratory - Cláudia Nunes dos Santos e Lucélia Tavares

• DROUGHTYRUS - Caracterização das respostas fisiológicas de espécies de Lathyrus ao deficit hídrico [pdf.]
  Plant Cell Biotechnology - Carlota Vaz Patto e Susana Araújo

• NUTICAEVOLVE - Evolução da diversidade genética na adaptação a largo prazo de germoplasma exótico de milho num projecto Português de conservação e melhoramento participativos [pdf.]
  Plant Cell Biotechnology - Carlota Vaz Patto

• How world climate changes can affect plant epi/genomes?
  GPlantS - Ana Paula Santos [pdf.]

   

Technology Divison

• Evaluation of bioactive extracts as promising natural chemotherapeutic agents- an in vitro approach [pdf.]
  Nutraceuticals and Delivery - Catarina Duarte

• Development of particulate systems for the delivery of ursodeoxycholic acid (and conjugates): strategies to overcame the BBB [pdf.]
  Nutraceuticals and Delivery - Catarina Duarte

• Preparation of novel gelatine-based drug delivery systems – application to model anti-inflammatory drug [pdf.] 
  Nutraceuticals and Delivery - Catarina Duarte

• Pharmacokinetics and Biopharmaceutical Analysis Laboratory - Ana Luísa Simplício

• Desenvolvimento de ELISA para diagnóstico de Theileria spp [pdf.]
  Biomolecular Diagnostics Laboratory - Abel Oliva

• Espectrometria de impedância aplicada à caracterização de células parasitadas numa plataforma de microfluídica [pdf.]
  Biomolecular Diagnostics Laboratory - Abel Oliva

full list of projects [*.pdf]