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Publications in Peer Reviewed Journals



  • M Roxo-Rosa; G Costa; TM Luider; BJ Scholte; AV Coelho; MD Amaral; D Penque “Proteomic analysis of nasal cells from Cystic Fibrosis patients and non-CF control individuals: search for novel biomarkers of CF lung disease”, Proteomics (2006) 6: 2314-25


  • MN Bravo, S Silva, AV Coelho, L Vilas Boas, MR Bronze “Production of Muscatel wines: Analysis of phenolic compounds by HPLC-DAD-FD-ED and MS” Analytica Chimica Acta, (2006) 563, 84-92


  • Coroadinha AS, Silva AC, Pires E, Coelho A, Alves PM, Carrondo MJ “The effect of osmotic pressure on the production of retroviral vectors: enhancement in vector stability.” Biotechnology and Bioengineering, (2006) 94, 322-329


  • Miranda J, Nascimento E, Cruz H, Hong Y, A Coelho, Ahmed J, Oliva A “Identification and characterization of merozoite antigens of a Theilerianbsp; species highly pathogenic for small ruminants in China.” Ann NYAcad Sci (2006),1081:443-452


  • S. Silva, L Gomes, F. Leitão, A V Coelho, L. Vilas Boas, “Phenolic compounds and antioxidant activity in Olea europaea L. fruits and leaves” Food Science and Technology International, (2006) 12, 385–396


  • F Li, R Delgado, A Coelho, MGB Drew and V Felix “New dioxadiaza-, trioxadiaza- and hexaaza-macrocycles containing dibenzofuran units” Tetrahedron (2006) 62, 8550–8558


  • R Gomes, H Vicente Miranda, M Sousa Silva, G Graça, A Coelho, A Ferreira, C Cordeiro, Ana Ponces Freire “Yeast protein glycation in vivo by methylglyoxal: Molecular modification of glycolytic enzymes and heat shock proteins” FEBS J. (2006);273(23):5273-87


  • Zhenjia C, Franco CF, Baptista RP, Cabral JMS, Coelho AV, Rodrigues CJ, Melo EP, “Purification and identification of cutinases from C kahawae and C gloesporioides” Applied Microbiology and Biotechnology, (2007), 73(6):1306-13


  • FM Valente, PM Pereira, SS Venceslau, M Regalla, AV Coelho and IA Pereira “The [NiFeSe] hydrogenase from D vulgaris Hildenborough is a bacterial lipoprotein lacking a typical lipoprotein signal peptide” FEBS Letters (2007); 581(18):3341-4


  • Santos SC, Vala I, Miguel C, Barata JT, Garção P, Agostinho P, Mendes M, Coelho AV, Calado A, Oliveira CR, e Silva JM, Saldanha C “Expression and subcellular localization of a novel nuclear acetylcholinesterase protein” JBC (2007); 282(35):25597-603


  • Gomes RA, Miranda HV, Sousa Silva M, Graça G, Coelho AV, do Nascimento Ferreira AE, Cordeiro C, Freire AP “Protein glycation and methylglyoxal metabolism in yeast: finding peptide needles in protein haystacks” FEMS Yeast Res (2008); 8(1): 174-181


  • Caldeira AT; Feio SS, Arteiro JM, Coelho AV, Roseiro JC “Environmental dynamics of B amyloliquefaciens CCMI 1051 antifungal activity under different nitrogen patterns” J Appl Microbiol (2008)104 (3):808-816


  • G da Costa, E Lamy, F Capela e Silva, J Andersen, E Sales Baptista, AV Coelho “Effect of tannin enriched diet on the expression of mouse salivary proteins” J Chem Ecology (2008) 34(3):376-87


  • E Lamy, G da Costa , F Capela e Silva, J Potes, A V Coelho, E Sales Baptista “Comparasion of Electrophoretic Protein Profile from Sheep and Goat Parotid Saliva” J Chem Ecology (2008) 34(3):388-97


  • M Mendes, S Mota, D Penque, A Coelho, C Cunha “Changes in the proteome of Huh7 cells induced by transient expression of hepatitis D virus RNA and antigens” J proteomics (2008);71(1):71-9


  • MCM Mellado, C Franco, A Coelho, PM Alves, AL Simplício “SDS-capillary gel electrophoresis analysis of rotavirus-like particles” J Chromatography A, (2008); 1192 (1); 166-172


  • Gomes RA, Oliveira LM, Silva MC, Ascenso C, Quintas A, Costa G, Coelho AV, Sousa Silva M, Ferreira AE, Ponces Freire A, Cordeiro C “Protein glycation in vivo: Functional and structural effects on yeast enolase” Biochem J. (2008), 416(3):317-26


  • Bravo MN, Feliciano R, Silva S, Coelho AV, Boas LV, Bronze MR “Analysis trans-resveratrol: Comparison of Methods and Contents in Muscatel Fortified Wines from Setubal Region in Portugal”, Journal of Food Composition and Analysis, 2008, 21(8), 634-643


  • Pereira L, Coelho AV, Viegas CA, dos Santos MMC, Robalo MP, Martins LO, Enzymatic Biotransformation of the Azo Dye “Sudan Orange G with Bacterial CotA-Laccase” Journal of Biotechnology (2009), 139(1):68-77


  • A M Almeida , S van Harten, A Campos, A V Coelho, L A Cardoso “The effect of weight loss on protein profiles of gastrocnemius muscle in rabbits: a study using 1D electrophoresis and Peptide Mass Fingerprinting”, J Animal Physiology and Animal Nutrition (2009) 87(2):196-9


  • R Santos, G da Costa, C Franco, P Alves, P Flammang, AV Coelho “First insights into the biochemistry of tube foot adhesive from the sea urchin Paracentrotus lividus (Echinoidea, Echinodermata)” Marine Biotechnology (2009), 11(6):686-98


  • S Mota, M Mendes, D Penque, N Freitas, AV Coelho, C Cunha “Proteome analysis of a human liver carcinoma cell line stably expressing hepatitis delta virus ribonucleoproteins” J Proteomics, (2009), 72(4):616-27


  • AM Almeida, A Campos, S van Harten, LA Cardoso, AV Coelho “Establishment of a proteomic reference map for the gastrocnemius muscle in the rabbit (Oryctolagus cuniculus)” Research in Veterinary Science (2009) 87(2):196-9


  • Toubarro D; Lucena-Robles M; Nascimento G; Costa G; Montiel R; Coelho AV; Simões N “An apoptosis-inducing serine protease secreted by the entomopathogenic nematode Steinernema carpocapsae” International Journal for Parasitology (2009) 39(12):1319-30


  • Marnoto Campos A; Costa G; Coelho A; Fevereiro P "Identification of bacterial protein markers and enolase as a plant response protein to infection of Olea europaea L. subsp. europaea by Pseudomonas savastanoi pv savastanoi" Eur J Plant Pathol (2009) 125(4), 603-616


  • Chaves I, Pinheiro C, Paiva JAP, Planchon S, Sergeant K, Renaut J, Graça JA, Costa G, Coelho AV, Ricardo CPP “Proteomic evaluation of wound-healing processes in potato (Solanum tuberosum L.) tuber tissue” Proteomics (2009) 9(17):4154-75.


  • Franco CF, Mellado MCM, Alves PM, Coelho AV “Monitoring virus-like particle and viral protein production by intact cell MALDI-TOF mass spectrometry” Talanta (2010) 80, 1561–1568


  • Lamy E, da Costa G, Santos R, Capela e Silva F, Potes J, Pereira A, Coelho AV, Sales Baptista E, “Sheep and goat saliva proteome analysis: A useful tool for ingestive behavior research?”, Physiology & Behavior (2009), 98(4):393-401


  • Gomes-Alves P, Neves S, Coelho AV, Penque D. “Low temperature restoring effect on F508del-CFTR misprocessing: A proteomic approach” J Proteomics (2009), 73(2):218-30


  • Pereira L, Coelho AV, Viegas CA, Ganachaud C, Iacazio G, Tron T, Robalo MP, Martins LO “On the Mechanism of Biotransformation of the Anthraquinonic Dye Acid Blue 62 by Laccases” Adv. Synth. Catal. (2009), 351, 1857 – 1865


  • A Campos, PK Carvajal-Vallejos, E Villalobos, CF Franco, AM Almeida, AV Coelho, JM Torne, M Santos “Characterisation of Zea mays L. plastidial transglutaminase: interactions with thylakoid membrane proteins” Plant Biology (2010), 12(5), 708 – 716


  • da Costa G, Gomes R, Correia CF, Freire A, Monteiro E, Martins A, Barroso E, Coelho AV, Outeiro TF, Ponces Freire A, Cordeiro C “Identification and quantitative analysis of human transthyretin variants in human serum by Fourier transform ion-cyclotron resonance mass spectrometry.” Amyloid (2009);16(4):201-7


  • Almeida AM, Campos A, Francisco R, van Harten S, Cardoso LA, Coelho AV “Proteomic investigation of the effects of weight loss in the gastrocnemius muscle of wild and NZW rabbits via 2D-electrophoresis and MALDI-TOF MS.” Anim Genet. (2010); 41(3):260-272


  • Perry MJ, Mendes E, Simplicio AL, Coelho, A, Soares RV, Iley J, Moreira R, Francisco AP “Dopamine- and tyramine-based derivatives of triazenes: Activation by tyrosinase and implications for prodrug design”, European Journal of Medicinal Chemistry, (2009), 44(8): 3228-3234


  • Matias A, Serra; Silva; Perdigão; Ferreira; Marcelino I; Silva S; Coelho A; Alves P; Duarte C “Portuguese winemaking residues as a potential source of natural anti-adenoviral agents” International Journal of Food Sciences and Nutrition (2010), 61(4):357-368


  • P Gomes-Alves; F Couto; C Pesquita; AV Coelho; D Penque “Rescue of F508del-CFTR by RXR-motif inactivation triggers proteome modulation associated with the unfolded protein response” BBA- Proteins and Proteomics (2010), 1804(4):856-865


  • S Silva, L Gomes, F Leitão, M Bronze, A V Coelho, L Vilas Boas “Secoiridoids in olive seed: characterization of nuzhenide and 11-methyl oleosides by liquid chromatography with diode array and mass spectrometry” Grasas y Aceites, (2010) 61 (2), 157-164


  • G da Costa, A Guerreiro, C F Correia, R J Gomes, A Freire, E Monteiro, E Barroso, A V Coelho, T F Outeiro, A Ponces Freire, C Cordeiro “A non-invasive method based on saliva to characterize TTR in FAP patients using FT-ICR high-resolution mass spectrometry“ Proteomics-Clinical Applications (2010) 4(6-7):674-678


  • E Lamy, G da Costa, R Santos, F Capela e Silva, J Potes, A Pereira, A V Coelho, E Sales Baptista “Effect of condensed tannin ingestion in sheep and goat parotid saliva proteome“ Journal of Animal Physiology and Animal Nutrition (2011), 95 (3), 304-312


  • A P Batista, C Franco, M Mendes, A V Coelho, M M Pereira “Subunit composition of Rhodothermus marinus respiratory complex I” Anal Biochem (2010) 407, 104-110


  • D Toubarro, M Lucena-Robles, G Nascimento, R Santos, R Montiel, A V Coelho, N Simões “A serine protease secreted by the parasitic nematode Steinernema carpocapsae is involved in host invasion” Journal Biological Chemistry, (2010) 285(40): 30666-30675


  • A M M Antunes, A L A Godinho, I L Martins, M C Oliveira, R A Gomes, A V Coelho, F A Beland, M M Marques “Protein adducts as prospective biomarkers of nevirapine toxicity” Chemical Research in Toxicology, (2010) 23 (11):1714–1725


  • M Puerto, A M Campos, A Prieto, A Cameán, A Almeida, A Coelho, V Vasconcelos “Differential protein expression in two bivalve species, Mytilus galloprovincialis and Corbicula fluminea, exposed to Cylindrospermopsis raciborskii cells” Aquatic Toxicology, (2011) 101(1):109-116


  • E Lamy, G Graça, G da Costa, C Franco, F Capela e Silva, E Sales Baptista, A V Coelho “Changes in mice whole saliva soluble proteome induced by tannin-enriched diet” Proteome Science (2010) 8:65


  • E Lamy, ES Baptista, AV Coelho, F Capela e Silva Morphological alterations in salivary glands of mice (Mus musculus) submitted to tannin enriched diets: comparison with sialotrophic effects of sympathetic agonists stimulation, Arq. Bras. Med. Vet. Zootec (2010) 62 (4), 837-844


  • CF Franco; R Santos; AV Coelho Exploring the proteome of an echinoderm nervous system: 2DE of the sea star radial nerve cord and the synaptosomal membranes subproteome, Proteomics (2011) 11(7), 1359-1364


  • E Lamy, H Rawel, F J. Schweigert, F Capela e Silva, A Ferreira, A R Costa, C Antunes, A M Almeida, AV Coelho, E Sales Baptista The Effect of Tannins in Mediterranean Ruminant Ingestive Behavior: The Role of Oral Cavity, Molecules, (2011), 16: 2766-2784; (Review article to special issue: Tannins)


  • M Mau, A Martinho de Almeida, AV Coelho, K-H Sudekum First identification of tannin-binding proteins in saliva of Papio hamadryas using MS/MS mass spectrometry American Journal of Primatology (2011) 73(9):896-902


  • AM Almeida, JR Parreira, R Santos, AS Duque, R Francisco, DFA Tomé, CP Ricardo, AV Coelho, PS Fevereiro A proteomics study of the induction of somatic embryogenesis in Medicago truncatula using 2DE and MALDI-TOF/TOF, Physiologia Plantarum (2012), 146: 236-249


  • CF Franco, R Santos, AV Coelho Proteome characterization of sea star coelomocytes – the innate immune effector cells of echinoderms, Proteomics (2011) 11(17):3587-92


  • LMA Oliveira, A Lages, RA Gomes, H Neves, C Familia, AV Coelho; A Quintas, Insulin glycation by methylglyoxal results in native-like aggregation and inhibition of fibril formation, Biochemistry (2011)12:41


  • Ribeiro-Silva C, Gilberto S, Gomes RA, Mateus L, Monteiro E, Barroso E, Coelho AV, da Costa GA, Freire AP, Cordeiro C The relative amounts of plasma transthyretin forms in familial transthyretin amyloidosis: A quantitative analysis by Fourier transform ion-cyclotron resonance mass spectrometry Amyloid. (2011)18(4):191-9


  • da Costa G, RA, Guerreiro A, Mateus E, Monteiro E, Barroso E, Coelho AV, Freire AP, Cordeiro C Beyond Genetic Factors in Familial Amyloidotic Polyneuropathy: Protein Glycation and the Loss of Fibrinogen's Chaperone Activity PLoS One. 2011;6(10):e24850


  • Caldeira, A T; Arteiro, J M S, Coelho, A V; Roseiro, J C Combined use of LC-ESI-MS and antifungal tests for rapid identification of bioactive lipopeptides produced by Bacillus amyloliquefaciens CCMI 1051, Process Biochemistry (2011) 46, 1738-1746


  • I Marcelino, A Martinho de Almeida, C Brito, DF Meyer, M Barreto, C Sheikboudou, CF Franco, D Martinez, T Lefrançois, N Vachiéry, MJT Carrondo, AV Coelho, PM Alves Proteomic analyses of Ehrlichia ruminantium highlight diferential expression of MAP1-family proteins in host endothelial cells, Veterinary Microbiology, (2012) 156(3-4), 305-14


  • I Marcelino, AM Almeida, M Ventosa, L Pruneau, DF Meyer, D Martinez, T Lefrançois, N Vachiéry, AV Coelho Tick-borne diseases in cattle: applications of Proteomics to develop new generation vaccines, J Proteomics, (2012) 75 (14): 4232-50 (Review article to special issue: Farm Animal Proteomics)


  • R Soares, C Franco, E Pires, M Ventosa, R Palhinhas, K Koci, AM Almeida, AV Coelho Mass Spectrometry and Animal Science: Protein identification strategies and particularities of farm animal species, J Proteomics, (2012) 75 (14): 4190-4296 (Review article to special issue: Farm Animal Proteomics)


  • AR Ribeiro, A Barbaglio, MJ Oliveira, R Santos, AV Coelho, CC Ribeiro, IC Wilkie, MD Candia Carnevali, MA Barbosa Correlations between the biochemistry and the mechanical states of the sea-urchin ligament: a mutable collagenous tissue. Biointerphases, (2012) 7, 38


  • Cal P; Vicente J; Pires E; Coelho A; Veiros L; Cordeiro C; Gois P Iminoboronates: A New Strategy for Reversible Protein Modification. Journal American Chemical Society (2012) 134 (24):10299-10305


  • A F Silva, G Carvalho, R Soares, A V Coelho, M T Barreto Crespo (2012) Step-by-step strategy for protein enrichment and proteome characterisation of extracellular polymeric substances in wastewater treatment systems Appl Microbiol Biotechnol (2012) 95:767–776


  • A Guerreiro, G da Costa, R A Gomes, C Ribeiro-Silva, S Gilberto, E Mateus, E Monteiro, E Barroso, A V Coelho, A Ponces Freire, C Cordeiro α-Synuclein aggregation in the saliva of familial transthyretin amyloidosis: a potential biomarker Amyloid, (2012) 19, (2), 74-80


  • T Rosado, P Bernardo, K Koci, AV Coelho, MP Robalo, LO Martins Methyl syringate: An efficient phenolic mediator for bacterial and fungal laccases Bioresource Technology 124 (2012) 371–378


  • CF Franco, R Soares, E Pires, R Santos, AV Coelho “Radial nerve cord protein phosphorylation dynamics during starfish arm tip wound healing events” Electrophoresis, 2012, 33, 3764–3778


  • LM Oliveira, RA Gomes, D Yang, SR Dennison, C Família, A Lages, AV Coelho, RM Murphy, DA Phoenix, A Quintas “Insights into the molecular mechanism of protein native-like aggregation upon glycation” Biochim Biophys Acta, 2012, doi:pii: S1570-9639(12)00271-3. 10.1016/j.


  • R Santos, A Barreto, C Franco, AV Coelho ”Mapping sea urchins tube feet proteome - A unique hydraulic mechano-sensory adhesive organ” J Proteomics, 2012, 79C, 100-113


  • A Campos, M Puerto, A Prieto, A Cameán, AM Almeida, AV Coelho, V Vasconcelos “Protein extraction and two-dimensional gel electrophoresis of proteins in the marine mussel Mytilus galloprovincialis: an important tool for protein expression studies, food quality and safety assessment” J Sci Food Agric. 2012 Nov 1. doi: 10.1002/jsfa.5977


  • RA Gomes, C Franco, G Da Costa, S Planchon, J Renaut, RM Ribeiro, F Pinto, MS Silva, AV Coelho, AP Freire, C Cordeiro “The proteome response to amyloid protein expression in vivo” PLoS One, 2012, 7(11):e50123. doi: 10.1371/journal.pone.0050123


  • C Franco, R Soares, E Pires, K Koci, A Almeida, R Santos, AV Coelho “Understanding Regeneration Through Proteomics” Proteomics, 2013, 13(3-4), 686-709 (Review article)


  • N Rainha, K Koci, A V Coelho, E Lima, J Baptista, M Fernandes-Ferreira “HPLC-UV-ESI-MS analysis of phenolic compounds and antioxidant properties of Hypericum undulatum Schousb. ex. Willd in vitro shoot cultures” Phytochemistry, 2013, 86:83-91


Book Chapters:

R Santos, E Hennebert, AV Coelho, P Flammang Functional, Surfaces in Biology- Cap “The echinoderm tube foot and its involvement in temporary underwater adhesion”, Editor S Gorb, Springer, 2009, pp.9-41

Sales Baptista E, Lamy E, Mau M, Capela e Silva F, Coelho AV, Behavioral and Chemical Ecology – Cap “Variation in salivary protein composition related to feeding behavior and its ecological implications” NOVA Publishers, 2009, pp 115-136

A Campos, AM Almeida, AV Coelho. Mitochondria: Structure, Functions and Dysfunctions – Cap “Blue Native PAGE, basis of the technique and its use in organelle study: the mitochondrial complexome. Mitochondria: Structure, Functions and Dysfunctions”. Edited by O.L. Svensson, Nova Science, Haupagge, NY, USA (2011) pp.975-982. ISBN:978-1-61668-346-7

Soares R, Pires E, Almeida AM, Santos R, Gomes R, Koči K, Franco CF, Coelho AV. Tandem Mass Spectrometry of peptides. In: Applications of Tandem Mass Spectrometry- its Principles and Applications, 2012 Jeevan K. Prasain (Ed.), ISBN: 978-953-51-0141-3, InTech.
Available from:

Cunha C, Coelho AV (2012). Comparative proteome analysis of a human liver cell line stably transfected with Hepatitis D virus full-length cDNA. In Liver Proteomics: Methods in Molecular Biology; Djuro Josic and Douglas C. Hixxon Eds. Humana Press, Volume 909, 205-225, DOI: 10.1007/978-1-61779-959-4_14.

  • published papers



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