Presentation Research Publications Facilities Group Contacts Vacancies
1. ß-D-ribopyranosides with Acetone,. N.A. Hughes and C.D. Maycock, Carbohydrate Research, 1974, 35, 247.

2. Simple Synthesis of Chiral Thiiranecarboxylic acids, C.D. Maycock and R.J. Stoodley, J.C.S. Chem. Commun., 1976, 234.

3. Studies Related to Thiirans. Part 1. Synthesis of Thiiranecarboxylates, C.D. Maycock and R.J. Stoodley, J.C.S. Perkin I, 1979, 1852.

4. (3R,4R)-4-t-Butylthio-3-phenylacetamidoazetidin-2-one, a Useful Precursor of Penicillin Analogues, A.C. Kaura, C.D. Maycock and R.J. Stoodley, J.C.S. Chem. Commun., 1980, 34.

5. Studies Related to Maytansinoids, D.H.R. Barton, S.D. Gero and C.D. Maycock, J.C.S. Chem. Commun., 1980, 1089.

6. Selectivities in the Reactions of Alkyl-, Aryl-, and Heterosubstituted Organotitanium Compounds, B. Weidmann, L. Widler, A. Olivera, C.D. Maycock and D. Seebach, Helvetica Chimica Acta, 1981, 64, 357.

7. Alkyl-, Aryl-, Vinyl-, and Heterosubstituted Organozirconium Compounds, - Selective Nucleophiles of Low Basicity, B. Weidmann, C.D. Maycock and D. Seebach, Helvetica Chimica Acta, 1981, 64, 1552.

8. Studies Related to Maytansinoids, D.H.R. Barton, S.D. Gero and C.D. Maycock, J.C.S. Perkin I, 1982, 1541.

9. Low Temperature Thermal Energy Storage Using Solid-state Phase Change Materials, M.C.P. Lima and C.D. Maycock, Energy Economics and Management in Industry, Eds. A. Reis, J.L. Peube, I. Smith and K. Stephan, Pergamon, Oxford, 1984, 151.

10. A Proton and 13C NMR Study of Keto-Enol Tautomerism of some ß-ketoamides. M.T. Barros, C.F. Geraldes, C.D. Maycock e M.I. Silva, Journal of Molecular Structure, 1986, 142 , 435.

11. The Reactivity of Silyl Ethers to the Swern Reagent, C. M. Afonso, M. Teresa Barros e Christopher D. Maycock. J.C.S., Perkin Trans. 1, 1987, 1221.

12. Studies Related to Penicillins Part 23. Preparation of Phenylacetyl and N-Triphenylmethyl Derivatives of (3R, 4R)-3-Amino-4-t-butylthioazetidin-2-one, J.C.S. Perkin Trans. I, 1987, 2009.

13. Studies Related to Penicillins Part 25. Synthesis of N-Phenylacetyl and N-Triphenylmethyl Derivatives of 6-Aminopenam 1-Oxides. J.C.S. Perkin I, 1988, 2259.

14. Formation and N.M.R. study of some cyclic ß-ketodithioacetals. C.F.C. Geraldes, M.T. Barros, M.I. Silva and C.D. Maycock, Tetrahedron, 1988, 44, 2283-7.

15. A Useful Method for Preparing Optically Active Secondary Alcohols: A Short Enantiospecific Synthesis of (R) and (S)-Sulcatol, C.M. Afonso, M.T. Barros, L. Godinho, C.D. Maycock., Tetrahedron Letters, 1989, 2707.

16. Solvent effects in the depolymerisation of poly-3-(R)-hydroxybutanoic acid (PHB), M.Teresa Barros, Christopher D. Maycock and Gil O. Santos, Rev. Port. Química. 1990, 32, 51.

17. The Preferential Direction of Enolisation of Some Asymmetric 1,3-Dicarbonyl Compounds in Solution. A Study by Multinuclear NMR Spectroscopy. C. Geraldes, M.T. Barros, C.D. Maycock and M.I. Silva, J. Mol. Struc., 1990, 238, 335.

18. Synthesis of 2,3-Dihydro-1,4-Dithiins and Alkylidene-1,4-Dithianes by 1,2-Sulphur Migration in 2-Hydroxyalkyldithioacetals, C.M. Afonso, M.T. Barros, L. Godinho, C.D. Maycock, Synthesis, 1991, 575.

19. An Application of Quinic Acid to the Synthesis of Linear Homochiral Molecules: A Synthesis of (+)-Negamycin, M.T.Barros, L.S.Godinho, C.D.Maycock, A.G.Santos, Tetrahedron Letters, 1992, 33, 4633.

20. Stereocontrolled Synthesis of the 4-Hydroxy-5-methyl-2-(3H)-Dihydrofuranone Isomers, C.A. Afonso, M.T. Barros, L.S. Godinho, C.D. Maycock, Tetrahedron, 1993, 49, 4283.

21. An Application of Quinic Acid to the Synthesis of Cyclic Homochiral Molecules: A Common Route to Some Interesting Carbocyclic Nucleoside Precursors, M.T.Barros, L.S.Godinho, C.D.Maycock, A.G.Santos, Tetrahedron Letters, 1993, 34, 7985.

22. A Flexible Synthesis of Some Polysubstituted Cyclopentanes From Quinic Acid, M.T. Barros, A.G. Santos, L.S. Godinho, C.D. Maycock, Tetrahedron Letters, 1994, 35, 3999.

23. The Mechanism of the Mitsunobu Azide Modification and the Effect of Additives on the Rate of Hydroxyl Group Activation, C.A. Afonso, M.T. Barros, L.S. Godinho, C.D. Maycock, Tetrahedron, 1994, 50, 9671.

24. On the Diastereoselectivity of the 1,2-Reduction of 2-Alkyl-4-Hydroxycyclopentenones with Sodium Borohydride in the Presence of Cerium (III): Synthesis of Prostaglandin Precursors, M. Teresa Barros, Cristina M. Alves, A. Gil Santos, Lício S. Godinho, Christopher D. Maycock, Tetrahedron Letters, 1995, 36, 2321.

25. Chiral Dithiolane Sulphoxides: An Efficient Stereoselective Synthesis of (R) and (S)-3-Benzoyloxy-2-butanone. M. Teresa Barros, Alcino J. Leitão and Christopher D. Maycock. Tetrahedron Letters, 1995, 36, 6537.

26. Chemoselectivity in the Manipulation of Polyhydroxylated Compounds Derived from the Diastereoselective Dihydroxylation of Optically Active Allylic Enoate Alcohols, M. Teresa Barros, M. Odile Januario-Charmier, Christopher D. Maycock and Mariana Pires.,Tetrahedron., 1996, 52, 7861.

27. Enantioselective Total Synthesis of (+)-Eutypoxide B, M. Teresa Barros, Christopher D. Maycock and M. Rita Ventura, J. Org. Chem., 1997, 62, 3984.

28. Enhanced Diastereo- and Enantioselectivity in the Formation of Acyldithiolane Sulfoxides by the Asymmetric Oxidation of their Enolsilyl Ethers. M. Teresa Barros, Alcino Leitão, and Christopher Maycock. Tetrahedron Letters, 1997, 38, 5047.

29. Synthesis of 2-Alkylidene-3,3-Dialkyl-1,4-Dithianes and their Oxathiane Analogues by 1,2-Sulphur Migration, M. Teresa Barros, Christopher D. Maycock and Lucia Santos. Heterocycles, 1998, 48, 1121.

30. Cutinase Activity and Enantioselectivity in Supercritical Fluids, Nuno Fontes M. Conceição Almeida, Célia Peres, Silvia Garcia, João Grave, M. Raquel Aires-Barros, Cláudio M. Soares, Joaquim M. S. Cabral, Christopher D. Maycock and Susana Barreiros. Industrial and Engineering Chemistry Research, 1998, 37, 3189.


31. Cutinase Activity and Enantioselectivity in Supercritical Fluids. Nuno Fontes, M. Conceição Almeida, Silvia Garcia, Célia Peres, João Grave, M. Raquel Aires-Barros, Cláudio M. Soares, Joaquim Cabral, Christopher Maycock and Susana Barreiros. Stability and Stabilization of Biocatalysts. A. Ballesteros, F. J. Plou, J. L. Iborra and P. J. Halling, Eds., Elsevier Science, 1998.

32. The Enantioselective Total Synthesis of Epoformin and Analogues, M. Teresa Barros, Christopher D. Maycock and M. Rita Ventura., Tetrahedron, 1999, 55, 3233.

33. The Effect of DMSO on the Borohydride Reduction of a Cyclohexanone: A Formal Enantioselctive Synthesis of (+)-Epibatidine, M. Teresa Barros, Christopher D. Maycock and M. Rita Ventura., Tetrahedron Letters, 1999, 40, 557.

34. The Synthesis of Shikimic acid and Derivatives from D-(-)-Quinic acid. Cristina Alves, M. Teresa Barros, Christopher D. Maycock and M. Rita Ventura., Tetrahedron, 1999, 55, 8443.

35. Azide Introduction During Stereoselective 1,2-Sulphur Migration in 2-Hydroxyalkyldithioacetals. Carlos A. Afonso, M. Teresa Barros and Christopher D. Maycock., Tetrahedron, 1999, 55, 801.

36. The Alkylation of a Novel Acetal Derived from (2R,3R)-(+)-Tartaric Acid: An Unexpected Rearrangement. M. Teresa Barros, Anthony J. Burke, and Christopher D. Maycock. Tetrahedron Letters, 1999, 40, 1583.

37. A First Synthesis of (-)-Asperpentyn and Efficient Syntheses of (+)-Harveynone, (+)-Epoformin and (-)-Theobroxide. M.T. Barros, C.D. Maycock, M.R. Ventura, Chem. Eur. J. 2000, 6, 3991.

38. Thermostabilization of Proteins by Diglycerol Phosphate, a New Compatible Solute from the Hyperthermophile Archeoglobus fulgidus, P. Lamosa, A. Burke, R. Peist, R. Huber, M-Y. Liu, G. Silva, C. Rodrigues-Pousada, J. LeGall, C. Maycock, H. Santos. Applied and Environmental Microbiology. 2000, 66, 1974.

39. Preparation of sucrose heptaesters unsubstituted at the C-1 hydroxy group of the sucrose moiety via selective O-desilylation, M.T. Barros, C.D. Maycock, C. Thomassigny, Carbohydrate Research. 2000, 328, 419.

40. Metabolism of [3-13C]Malate in Primary Cultures of Mouse Astrocytes, P. M. Alves, R. Nunes, C. Zhang, C. D. Maycock, U. Sonnewald, M. J. T. Carrondo & H. Santos, Developmental Neuroscience, 2000, 22, 456-462.

41. Fast galloylation of a sugar moiety: Preparation of three monogalloylsucroses as references for antioxidant activity. A method for the selective deprotection of tert-butyldiphenylsilyl ethers. M.T. Barros, C.D. Maycock, C. Thomassigny, F. Sineriz. Tetrahedron. 2000, 56, 6511.

42. Approaches to the Synthesis of (+)- and (-)-Epibatidine. M.T. Barros, C.D. Maycock, M.R. Ventura, JCS. Perkin trans I, 2001, 166.

43. The Effect of Diethylamine on Stille Alkylations with Tetraalkylstannanes. Barros, M. T.; Maycock, C. D.; Madureira, M. I.; Ventura, M. R., J. Chem. Soc. Chem. Commun. 2001, 1662.

44. Bromine in Methanol: An Efficient Reagent for the Deprotection of the tert-Butyldiphenylsilyl Group. Barros, M. T.; Maycock, C. D.; Thomassigny, C. Synlett. 2001, 7, 1146-1148.

45. An Expedient Stereoselective Synthesis of Polysubstituted Piperidin-2-ones. Barros, M. T.; Januário-Charmier, M. A.; Maycock, C. D.; Michaud, T. Tetrahedron, 2002, 58, 1519-1524.

46. A Synthesis of Aziridines from ?-Iodocycloenones. M.T. Barros, C.D. Maycock, M.R. Ventura, Tetrahedron. Lett., 2002, 43, 4329.

47. Stereoselective Radical Reactions of L-(+)-Tartaric and L-Glyceric Acid Derivatives. M.T. Barros, C.D. Maycock, M.R. Ventura, Org. Lett., 2002, 4, 2035.

48. Is the glycolytic flux in Lactococcus lactis primarily controlled by the redox charge? Kinetics of NAD+ and NADH pools determined in vivo by 13C-NMR, Neves, A. R.; Ventura, R.; Mansour, N.; Shearman, C.; Gasson, M. J.; Maycock, C.; Ramos, A.; Santos, H., Journal of Biological Chemistry 2002, 277, 28088.

49. Synthesis and Some Reactions of 2-Acyl-2-alkyl-1,3-dithiolane 1,1-Dioxides. M.T. Barros, A.S. Henriques, A.J. Leitão, C.D. Maycock. Helv. Chim. Acta, 2002, 85, 4079.

50. Aldol Reactions of Dioxanes Derived from Tartaric Acid. A Total Synthesis of (+)-Nephrosteranic Acid Barros, M. T.; Maycock, C. D.; Ventura, M. R., Org. Lett. 2003, 5, 4097.

51. Aziridines as a Protecting and Directing Group. Stereoselective Synthesis of (+)-Bromoxone, Barros, M. T.; Maycock, C. D.; Ventura, M. R., Org. Lett. 2003, 5, 4321.

52. Photochemistry of Flavothione and Hydroxyflavothiones: Mechanisms and Kinetics, António L. Maçanita, Fausto Elisei, Gian Gaetano Aloisi, Fausto Ortica, Vasco Bonifácio, António Dias, Emília Leitão, Maria João Caldeira, Christopher D. Maycock and Ralph S. Becker; Photochemistry and Photobiology 2003, 77, 22-29.

53. Protein Stabilization by Compatible Solutes: Effect of Diglycerol Phosphate on the Dynamics of Desulfovibrio gigas Rubredoxin Studied by NMR, Lamosa, P.; Turner, D. L.; Ventura, R.; Maycock, C.; Santos, H. Eur. J. Biochem. 2003, 270, 4606.

54. Improved anomeric selectivity for the aroylation of sugars; M. Teresa Barros, Christopher D. Maycock, Paula Rodrigues and Christine Thomassigny; Carbohydr. Res. 2004, 339, 1373-1376

55. Novel cyclic 1,2-diacetals derived from (2R,3R)-(+)-tartaric acid: synthesis and application as N,O-ligands for the enantioselective alkylation of benzaldehyde by diethylzinc; M. T. Barros; C. D. Maycock; A. M. Faisca Phillips; Eur. J. Org. Chem. 2004, 8, 1820-1829

56. The effect of pyruvate kinase overproduction on glucose metabolism of Lactococcus Lactis, Ana Ramos, Rute Neves, Rita Ventura, Christopher Maycock, Paloma López and Helena Santos; Microbiology 2004, 150, 1103.

57. Intramolecular Fluorescence Quenching of Tyrosine by the Peptide alpha-Carbonyl Group Revisited; M. Noronha, J.C. Lima, P. Lamosa, H. Santos, C.D. Maycock, R. Ventura, and A.L. Maçanita; J Phys Chem A, 2004, 108, 2155.

58. Highly Stereoselective Aldol Reaction for the Synthesis of gama-Lactones Starting from Tartaric Acid, Barros, M. T.; Burke, A. J.; Lou, J.-D.; Maycock, C. D.; Wahnon, J. R.; J. Org. Chem. 2004, 108, 2155-2166.

59. Stereoselective Synthesis of Optically Active Mono and Diaminoalcohols. M. Teresa Barros, M. Adilia Charmier, Christopher D. Maycock and Thierry Michaud, Tetrahedron, 2005, 61, 7960-7966.

60. Novel Chiral Bis(oxazolines): Synthesis and Application as ligands in the Copper Catalysed Enantioselecive Conjugate Addition of Diethylzinc to Enones, M. Teresa Barros, Christopher D. Maycock and Ana Maria Faisca Phillips, Tetrahedron Asymmetry, 2005, 16, 2946-2953.

61. Burke, A. J.; Maycock, C. D.; Ventura, M. R., “Stereoselective Alkylation of Tartrate Derivatives. A Concise Route to (+)-Piscidic Acid and Natural Analogues" Org. Biomol. Chem. 2006, 4, 2361.

62. Borges, N; Gonçalves, L. G.; Rodrigues, M. V.; Siopa, F.; Ventura, R.; Maycock, C.; Lamosa, P.; Santos, H. “The Biosynthetic Pathways of Inositol and Glycerol Phosphodiesters used by the Hyperthermophile Archaeoglobus Fulgidus in Stress Adaptation” Journal of Bacteriology 2006, 188, 8128.

63. Marta V. Rodrigues, Nuno Borges, Mafalda Henriques, Pedro Lamosa, Rita Ventura, Chantal Fernandes, Nuno Empadinhas, Christopher Maycock, Milton S. da Costa, and Helena Santos, Bifunctional CTP:Inositol-1-Phosphate Cytidylyltransferase/CDP-Inositol:Inositol-1-Phosphate Transferase, the Key Enzyme for Di-myo-Inositol-Phosphate Synthesis in Several (Hyper)thermophiles, Journal of Bacteriology2007, 189, 5405-5412.

Patent

"Thermostabilisation, Osmoprotection, and Protection Against Desiccation of Enzymes, Cell Components and Cells by di-Glycerol-phosphate. H. Santos, P. Lamosa, A. Burke & C. Maycock. Ref. Application No. 98 670 002.9-2110

"Derivados sintéticos de manosil-glicerato para a estabilização e/ou preservação de biomateriais". P. Lamosa, T. Q. Faria, M. R. Ventura, C. D. Maycock, H. Santos. Patente PAT 103442 P; 2006/02/24. Requerente: STAB VIDA, Lda.

ITQB UNL