Chemistry Division Seminar
Lanthanide(III) complexes of phosphorus-containing cyclen derivatives: structural aspects and their implications for design of MRI contrast agents and bone targeting ligands.
| When |
24 Apr, 2008
from
12:00 pm to 02:00 pm |
|---|---|
| Where | Auditorium |
| Speaker(s) |
Petr Hermann University Karlova (Charles University), Prague, Czech |
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Chemistry Division Seminar
Title: Lanthanide(III) complexes of phosphorus-containing cyclen derivatives: structural aspects and their implications for design of MRI contrast agents and bone targeting ligands.
Abstract:
An influence of phosphonic or phosphinic acid pendant arm(s) in DOTA-like ligands on structures of lanthanide(III) complexes, both in solution and in the solid state, will be presented. Resulting physico-chemical parameters important for MRI contrast agents (water residence life-time, rotation correlation time, hydration) will be also discussed. Bone targeting of the complexes will be exemplified on bis(phosphonate) derivatives of the cycles. For more information see
http://www.natur.cuni.cz/anorchem/19/index.htm .
Speaker: Petr Hermann
Affiliation: Department of Inorganic Chemistry, University Karlova (Charles University), Prague, Czech
Host: Prof. Rita Delgado
