[Seminar] Three types of cell competition and their roles during ageing, cancer and development
Eduardo Moreno, Cell Fitness Lab, Champalimaud Centre for the Unknown
| When |
02 Feb, 2017
from
02:00 pm to 03:00 pm |
|---|---|
| Where | Auditorium |
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Seminar
Title: Three types of cell competition and their roles during ageing, cancer and development
Speaker: Eduardo Moreno
Affiliation: Cell Fitness Lab, Champalimaud Centre for the Unknown
Host: Pedro Domingos Lab - Cell Signaling in Drosophila
Abstract:
Humans are able to detect fitness decay in colleagues by looking at the graying of the hair or the wrinkles in their faces. Work from my laboratory in the last few years has shown that cells can also detect fitness levels of neighboring cells using a molecular code. Those "fitness fingerprints" (Rhiner et al., Dev.Cell, 2010; Merino et al., Curr. Biol., 2013) can be used to mediate cell selection by recognizing and eliminating less fit cells during ageing (Merino et al., Cell, 2015), regeneration (Moreno et al., Curr. Biol., 2015) and cancer (Levayer et al., Nature 2015).
Webpage: http://neuro.fchampalimaud.org/en/research/investigators/research-groups/group/Moreno/
