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Cancer research

A large number of anticancer drugs fail in clinical trials due to lack of efficacy. To increase the number of well succeeded drug candidates, more predictive models for pre-clinical discovery are required. Tumour cell lines are adapted to proliferate in 2D culture dishes, which fail to recapitulate physiological cell-cell, cell-matrix and other microenvironment contacts.

We are working on the development of 3D in vitro cancer models that better mimic solid tumours by conjugating bioreactor technology and multicellular aggregate approaches.

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