[SCAN] Coordination of chromosome segregation and daughter cells separation in Staphylococcus aureus
Helena Veiga
| When |
21 Jul, 2021
from
12:00 pm to 01:00 pm |
|---|---|
| Contact Name | Rita Abranches |
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Title: Coordination of chromosome segregation and daughter cell separation in Staphylococcus aureus
Speaker: Helena Veiga
Abstract: The generation of equal progeny after a bacterium division cycle is contingent on the accurate and synchronized occurrence of four major processes: (1) replication/segregation of the genetic material, (2) septum assemble/maturation at the correct division site, (3) septum constriction and (4) hydrolysis, at the precise time and place, of peptidoglycan (PG) - the cell-wall material synthesized by the division machinery - to physically separate the two daughter cells. For all these processes to be tightly regulated in time and space, the existence of regulators and/or checkpoints is of extreme importance. Here we identify a previously unknown checkpoint in bacterial cell cycle progression, linking chromosome segregation to the final step of division, the splitting of the two daughter cells.
