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Funded projects

1997-1999  Construction of stable animal cells expressing chimeric forms of human fucosyltransferase III. Study of the intracellular transport of the enzyme, FCT, Portugal (PI).

1999-2001  Mucin O-glycosylation in human gastric mucosa, intestinal metaplasia, gastric carcinoma and gastric cancer cell lines: role of glycosyltransferases and of the carrier proteins; FCT. Collaboration with L. David (PI), IPATIMUP, Oporto. 

2000-2002  Human fucosyltransferases: membrane organization and regulation of the in vivo activity, FCT, Portugal (PI). 

2001-2005  Purification, gene cloning and characterization of plant fucosyltransferases, FCT, POCTI/BIO/35679/2000 (PI). 

2002-2005  Identification and characterization of proteins involved in Golgi organization from mammalian cells, FCT, POCTI/BCI/38631/2001 (PI). 

2003-2005  Clinical, neurophysiological and neurochemical studies in Amyotrophic Lateral Sclerosis, FCT, POCTI/CBO/43952/02. Collaboration with M. de Carvalho (PI), IMM, Faculty of Medicine, University of Lisbon (FML). 

2004-2007  Signalling and Membrane Trafficking in Transformation and Differentiation, STREP, European Sixth Framework Program, LSHG-CT-2004-503228. PI of the Portuguese team. Project coordinator: T. Galli, INSERM, Paris. 

2004-2008  Cell Programming by Nanoscaled Devices, Integrated Project, European Sixth Framework Programme, nº 500039-2. Collaboration with M. Carrondo (PI of the Portuguese team), IBET, Oeiras. Project coordinator: G. Fuhr, Fraunhofer, Institute for Biomedical Engineering IBMT, Germany. 

2007-2009  Study of the biological role of ADAM10 N-linked oligosaccharides. Bilateral collaboration CRUP/DAAD, ref. A-8/07. Collaboration with P. Altevogt, DKFZ, Germany. 

2008-2010  Associated participant of BBMRI / Biobanking and Biomolecular Resources Research Infrastructure. Combination of Collaborative Project and Coordination and Support Actions, European Seventh Framework Programme, nº 212111. Project coordinator: K. Zatloukal, Medical University of Graz.

2009-2012  Respiratory Rehabilitation in Amyotrophic Lateral Sclerosis: clinical and biochemical impact, FCT, PIC/IC/82765/2007. Collaboration with M. de Carvalho (PI), IMM, Faculty of Medicine, University of Lisbon. 

2009-2014  The EuroGlycosciences Forum (Euroglycoscience) network, European Science Foundation. Project coordinator: S.L. Flitsch, University of Manchester.

2010-2013  Glycosylation and Lewis X motif in neuronal tissue, FCT, PTDC/SAU-NEU/100724/2008 (PI). 

2012-2016  Sampling and biomarker OPtimization and Harmonization In ALS and other motor neuron diseases (SOPHIA), EU Joint Programming Neurodegenerative Disease (JPND) Research, FCT, JPND/0003/2011 (PI). Project coordinator: L.H. van den Berg, University Medical Center Utrecht, The Netherlands. 

2014-2018  Nanoengineered exosomes to treat glioma (GlioEx), EURONANOMED II, FCT, ENMed/0001/2013 (PI). Project coordinator: M. Glatzel, University Medical Center Hamburg‐Eppendorf, Germany. 

2015-2017  Participation in the Research Unit iNOVA4Health - Advancing Precision Medicine, FCT/Ministério da Educação e Ciência, FEDER, LISBOA-01-0145-FEDER-007344. Coordinator of Research Group 4 (Biomarkers and Diagnostics).

2015-2017  mioSpA: the role of the muscle in Spondyloarthritis, a new paradigm. Collaborative project in context of iNOVA4Health Research Unit, with Fernando Pimentel-Santos (project coordinator).

2020-2021  Muscle up with intermittent hypoxia: a matter of intensity, gender and metabolism. iNOVA4Health, FCT. Collaboration.

2020-2021  Investigating GLT8D1 specificity and its implications in brain disease. Exploratory Project iBET. iNOVA4Health (PI). 

2018-2023  Participation in the Research Unit iNOVA4Health, UIDB/04462/2020, FCT/Ministério da Educação e Ciência, FEDER.

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