Publications

 Papers in international peer-reviewed journals

 2016  2015  2014  2013  2012  2011 <2010  

 2016

• Feliciano RP, Boeres A, Massacessi L, Istas G, Ventura MR, Nunes Dos Santos C, Heiss C, Rodriguez-Mateos A. (2016) Identification and quantification of novel cranberry-derived plasma and urinary (poly)phenols. Arch Biochem Biophys. 599, 31-41. (doi:10.1016/j.abb.2016.01.014).

• Matias AA, Rosado-Ramos R, Nunes S, Figueira I,  Serra AT, Bronze MR, Santos CN, Duarte CMM (2016) Protective Effect of a (Poly)phenol-Rich Extract Derived from Sweet Cherries Culls against Oxidative Cell Damage.  Molecules 2016, 21, 406. (DOI:10.3390/molecules21040406)

• Feliciano RP, Boeres A, Massacessi L, Istas G, Ventura MR, Nunes Dos Santos C, Heiss C, Rodriguez-Mateos A (2016) Identification and quantification of novel cranberry-derived plasma and urinary (poly)phenols. Arch Biochem Biophys. (DOI: 10.1016/j.abb.2016.01.014.)

• Klionski D, et al, Menezes R, et al, Santos CN, et al (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2012 Apr;8(4):445-544  Landes Bioscience. (DOI:10.4161/auto.19496).

 2015

• Lotti Egger, Olivia Ménard, Cristina Delgado-Andrade, Paula Alvito, Ricardo Assunção, Simon Balance, Reyes Barberá, Andre Brodkorb, Thomas Cattenoz, Alfonso Clemente, Irene Comi, Didier Dupont, Guadalupe Garcia-Llatas, María Jesús Lagarda, Steven Le Feunteun, Lonneke JanssenDuijghuijsen, Sibel Karakaya, Uri Lesmes, Alan R. Mackie, Carla Martins, Anne Meynier, Beatriz Miralles, Brent S. Murray, Anne Pihlanto, Gianluca Picariello, Claudia N. Santos, Sebnem Simsek, Isidra Recio, Neil Rigby, Laurie-Eve Rioux, Helena Stoffers, Ana Tavares, Lucelia Tavares, Sylvie Turgeon, Ellen K. Ulleberg, Gerd E. Vegarud, Guy Vergères, Reto Portmann (2015) The harmonized INFOGEST in vitro digestion method: From knowledge to action. Food Research International, ISSN 0963-9969. (DOI:10.1016/j.foodres.2015.12.006)

• Menezes R, Tenreiro S, Macedo D, Santos CN & Outeiro TO (2015). From the baker to the bedside: yeast models of Parkinson's disease. Microbial Cell 2:262. (DOI:DOI: 10.15698/mic2015.08.219)

• Mazzola D, Pimentel C, Caetano S, Amaral C, Menezes R, Santos CN, Eleutherio E & Rodrigues-Pousada C (2015). Inhibition of Yap2 activity by MAPKAP kinase Rck1 affects yeast tolerance to cadmium. FEBS Lett. 589:2841. (DOI: 10.1016/j.febslet.2015.07.049)

• Rémond, D; Shahar, DR; Gille D; Pinto P; Kachal, J; Peyron, MA; Santos, CN; Wallther, B; Bordoni, A; Dupont, D; Tomás-Cobos, L; Vergeres G. 2015. Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition. Oncotarget, Advance Publications. (DOI:  10.18632/oncotarget.4030)

• Bohn T, McDougall GJ, Alegría A, Alminger M, Arrigoni E, Aura A-M, Brito C, Cilla A, El SN, Karakaya S, Martínez-Cuesta MC, Santos CN (2015), Mind the gap—deficits in our knowledge of aspects impacting the bioavailability of phytochemicals and their metabolites—a position paper focusing on carotenoids and polyphenols. Mol Nutr Food Res, 59, 1307-23. (DOI: 10.1002/mnfr.201400745)

• Gomes, A., Pimpão, R. C., Fortalezas, S.; Figueira, I., Miguel, C. l.; Aguiar, C., Salgueiro, L., Cavaleiro, C., Gonçalves, M. J., Clemente, A., Costa, C.; Martins-Loução, M. A. l.; Ferreira, R. B.; Santos, C. N. (2015) Chemical characterization and bioactivity of phytochemicals from Iberian endemic Santolina semidentata and strategies for ex situ propagation. Industrial Crops and Products 74, 505-513 (DOI:10.1016/j.indcrop.2015.04.037)

• Macedo D, Tavares L, McDougall GJ, Vicente Miranda H, Stewart D, Ferreira RB, Tenreiro S, Outeiro TF, Santos CN (2015) (Poly)phenols protect from alpha-synuclein toxicity by reducing oxidative stress and promoting autophagy. Hum. Mol. Genet., 2015, Vol. 24, No.6 1717–1732 (DOI:10.1093/hmg/ddu585)

• A Bordoni, A; Danesi, F; Dardevet, D; Dupont, D; Fernandez, A; Gille, D; Santos, CN; Pinto, P; Re, R; Rémond, D; Shahar, D; Vergéres, G. 2015. Dairy products and inflammation: a review of the clinical evidence. Critical Reviews in Food Science and Nutrition. (DOI:10.1080/10408398.2014.967385) 

• Rui C. Pimpão, M. Rita Ventura, Ricardo B. Ferreira, Gary Williamson and Claudia N. Santos, (2015) Phenolic sulfates as new and highly abundant metabolites in human plasma after ingestion of a mixed berry fruit purée, British Journal of Nutrition, available on CJO2015. (DOI:10.1017/S0007114514003511)

 2014

• M. Alminger, A.-M., Aura, T. Bohn, C. Dufour, S.N. El, A. Gomes S., Karakaya, M.C. Martínez-Cuesta, G.J. McDougall, T. Requena, C.N. Santos, (2014) In vitro Models for Studying Secondary Plant Metabolite Digestion and Bioaccessibility, Comprehensive Reviews in Food Science and Food Safety (DOI: 10.1111/1541-4337.12081)
• Minekus, M., Alminger, M., Alvito, P., Ballance, S., Bohn, T., Bourlieu, C., Carriere, F., Boutrou, R., Corredig, M., Dupont, D., Dufour, C., Egger, L., Golding, M., Karakaya, S., Kirkhus, B., Le Feunteun, S., Lesmes, U., Macierzanka, A., Mackie, A., Marze, S., McClements, D.J., Menard, O., Recio, I., Santos, C.N., Singh, R.P., Vegarud, G.E., Wickham, M.S.J., Weitschies, W. & Brodkorb, A. (2014) A standardised static in vitro digestion method suitable for food - an international consensus. Food Funct. (DOI: 10.1039/C3FO60702J)
• Tenreiro, S.; Reimão-Pinto, M.M.; Antas, P.; Rino, J.; Wawrzycka, D.; Macedo, D.; Rosado-Ramos, R.; Amen, T.; Waiss, M.; Magalhães, F.; Gomes, A.; Santos, C.N.; Kaganovich, D; Outeiro, T.F. (2014) Phosphorylation Modulates Clearance of Alpha-Synuclein Inclusions in a Yeast Model of Parkinson's Disease. PLoS Genetics  (DOI:10.1371/journal.pgen.1004302) 
• Pimpão, R.C.; Dew, T.; Figueira, M. E.; McDougall, G. J.; Stewart, D.; Ferreira, R. B.; Santos, C. N.; Williamson, G. (2014) Urinary metabolite profiling identifies novel colonic metabolites and conjugates of phenolics in healthy volunteers. Molecular Nutrition & Food Research (DOI: 10.1002/mnfr.201300822)
• Pimentel, C.; Caetano, S.M.; Menezes, R.; Figueira, I.; Santos, C.N.; Ferreira, R.B.; Santos, M.A.; Rodrigues-Pousada, C. (2014) Yap1 mediates tolerance to cobalt toxicity in the yeast Saccharomyces cerevisiae. Biochimica et Biophysica Acta (BBA) - General Subjects (DOI:10.1016/j.bbagen.2014.01.032.)

  2013

• Gomes, A.; Fortalezas, S.; Pimpão, R.; Figueira, I.; Maroco, J.; Aguiar, C.; Ferreira, R.B.; Miguel, C.; Santos, C.N. (2013) Valuing the Endangered Species Antirrhinum lopesianum: Neuroprotective Activities and Strategies for in vitro Plant Propagation. Antioxidants (DOI:10.3390/antiox2040273)

• Pinto, P., Cardoso, S., Pimpão, R.C., Tavares, L., Ferreira, R.B., Santos, C.N. (2013) Daily polyphenol intake from fresh fruits in Portugal: contribution from berry fruits. International Journal of Food Sciences and Nutrition  (DOI:10.3109/09637486.2013.816938).
• Tavares, L., Pimpão, R., McDougall, G., Stewart, D., Ferreira, R. B., and Santos, C. N. (2013) Elucidating phytochemical production in Juniperus sp.: seasonality and response to stress situations. Journal of Agricultural and Food Chemistry 61 (17) 4044-4052.
• Pimpão, R. C., Dew, T., Oliveira, P. B., Williamson, G., Ferreira, R. B., and Santos C. N. (2013) Analysis of phenolic compounds in Portuguese wild and commercial berries after multi-enzyme hydrolysis. Journal of Agricultural and Food Chemistry 61 (17) 4053-4062.
• Santos, C. N., Alves, M., Oliveira, A. and Ferreira, R. B. (2013) β-N-Acetylhexosaminidase involvement in α-conglutin mobilization in Lupinus albus. Jornal of Plant Physiology 170 (12): 1047-1056.
• Tavares, L., Figueira, I., McDougall, G. J., Vieira, H. L. A., Stewart, D., Alves, P. M., Ferreira R. B. and Santos C. N. (2013) Neuroprotective effects of digested polyphenols from wild blackberry species. European Journal of Nutrition 52 (1): 225-236.

  2012

• Santos, C. N., Alves, M., Bento, I., Ferreira, R. B. (2012) Missing pieces in protein deposition and mobilization inside legume seed storage vacuoles: calcium and magnesium ions. Seed Science Research 22: 249-258.
• Tavares, L., McDougall, G. J., Fortalezas, S., Stewart, D., Ferreira, R. B., Santos, C. N. (2012) The neuroprotective potential of phenolic-enriched fractions from four Juniperus species found in Portugal. Food Chemistry 135 (2): 562–570.
• Tavares, L., Fortalezas, S., Tyagi, M., Barata, D., Serra, T., Duarte, C., Duarte, R., Feliciano, R., Bronze, M. R., Espírito-Santo, M. D., Ferreira, R. B. and Santos, C. N. (2012) Bioactive compounds from endemic plants of Southwest Portugal: Inhibition of acetylcholine esteraseand radical scavenging activities. Pharmaceutical Biology, 50 (2): 239-246.
• Tavares, L., Figueira, I., Macedo, D., McDougall, G. J., Leitão, M. C., Vieira, H. L. A., Stewart, D., Alves, P. M., Ferreira, R. B., Santos, C. N. (2012) Neuroprotective effect of blackberry (Rubus sp.) polyphenols is potentiated after simulated gastrointestinal digestion. Food Chemistry, 131 (4): 1443-1452.

 2011

• Tavares, L., Alves, P. M., Ferreira, R. B. and Santos, C. N. (2011) Comparison of different methods for DNA-free RNA isolation from SK-N-MC neuroblastoma. BMC Research Notes, 1: 140

 <2010

• Monteiro, S., Freitas, R., Rajasekhar. B.T., Teixeira, A.R. and Ferreira, R.B. (2010) The unique biosynthetic route from Lupinus β-conglutin gene to blad. PLoS ONE 5(1): e8542.
• Fortalezas, S., Tavares L., Pimpão R., Tyagi, M., Pontes, V., Alves, P.M., McDougall, G., Stewart, D., Ferreira, R.B. and Santos, C.N. (2010) Antioxidant properties and neuroprotective capacity of strawberry tree fruit (Arbutus unedo). Nutrients, 2 : 214-229;
• Tavares, L., Carrilho, D., Tyagi, M., Barata, D., Serra, A.T., Duarte, C.M.M., Duarte, R.O., Feliciano, R.P., Bronze, M.R., Chicau, P., Espírito-Santo, M.D., Ferreira, R.B. and dos Santos, C.N. (2010). Antioxidant Capacity of Macaronesian Traditional Medicinal Plants. Molecules , 15: 2576-2592.
• Tavares, L., Fortalezas, S., Carrilho, C., McDougall, G.J., Stewart D., Ferreira R.B., Santos C. (2010) Antioxidant and antiproliferative properties of strawberry tree tissues. Journal of Berry Research, 1: 3-12.
• Cherian, S. and Ferreira, R.B. (2010) Analysis of Lupinus albus heat-shock granule proteins in response to high temperature stress. Biologia Plantarum, 54: 587-591.

• Menezes, R.A., Amaral, C., Batista-Nascimento, L., Santos, C., Ferreira, R.B., Devaux, F., Eleutherio, E. and Rodrigues-Pousada, C. (2008) Contribution of Yap1 towards S. cerevisiae adaptation to arsenic mediated oxidative stress. Biochemistry Journal. 414: 301–311.
• Ferreira, R.B., Monteiro, S., Freitas, R., Santos, C.N., Chen, Z., Batista, L.M., Duarte, J., Borges, A. and Teixeira, A.R. (2007) The role of plant defence proteins in fungal pathogenesis. Molecular Plant Pathology, 8 : 677-700. (review article)
• Ferreira, R.B., Monteiro, S., Freitas, R., Santos, C.N., Chen, Z., Batista, L.M., Duarte, J., Borges, A. and Teixeira, A.R. (2006) Fungal pathogens: The battle for plant infection. Critical Reviews in Plant Sciences, 25 : 505-524. (review article)
• Santos, C., Caeiro, A.S., Branco-Price, C., Teixeira, A.R. and Ferreira, R.B. (2006)  Exposure of Lemna minor to arsenite: espression levels of the components and intermediates of the ubiquitin/proteasome pathway. Plant and Cell Physiology, 47 : 1262-1273.

Chapters in Books

• Ferreira, R.B., Monteiro, S., Freitas, R., Santos, C.N., Chen, Z., Batista, L.M., Duarte, J., Borges, A. and Teixeira, A.R. (2008) Plant/fungal interactions studied at the molecular level. In: Plant pathology concepts and laboratory exercises. 2nd Edition. Chapter 28, pp. 309-322. R.N.Trigiano, M.T. Windham and A.S. Windham, Eds. CRC Press, Boca Raton.
• Monteiro, S., Batista, L., , Loureiro, V., Teixeira, A. and Ferreira, R.B. (2007) Major characteristics of wine proteins. In: Macromolecules and secondary metabolites of grapevine and wine, (P. Jeandet, C. Clément and A. Conreaux), pp. 153-158. Lavoisier, Paris.

Oral Communications by invitation

• Santos, C., Tavares, L., Pontes, V., Alves, P. and Ferreira, R.B. (2008) Antioxidant capacity of portuguese endemic Rubus fruits in a neurodegeneration cell model. Workshop on Bioactive compounds in berry fruits: genetic control, breeding, cultivar, analytical aspects and human health, Zurich, Switzerland, pp. 33.
• Tavares, L., Santos, C., McDougall, G., Stewart, D. and Ferreira, R.B. (2008) Portuguese endemic wild blackberries as an alternative source of polyphenols and antioxidant activity. Workshop on Bioactive compounds in berry fruits: genetic control, breeding, cultivar, analytical aspects and human health, Zurich, Switzerland, pp. 19.

Abstracts in international scientific periodicals with referees 

• Tavares,L., R.C. Pimpão, C. Santos, G.J. McDougall, D. Stewart and R.B. Ferreira. (2009). Phytochemical characterization of Juniperus spp. leaves. 57th International Congress and Annual Meeting of the GA. August 16 – 20, Geneva, Switzerland. Planta Medica 75: 923.
• Santos, C., Tavares, L., Fortalezas, S., Carillho, D., Pontes, V., McDougall G. J., Stewart, D. and Ferreira, R. B. (2009). Neuroprotective and MMP-9 inhibitory activity of hydroethanolic extract of Arbustus unedo leaves. 57th International Congress and Annual Meeting of the GA. August 16 – 20, Geneva, Switzerland. Planta Medica 75: 924.

Papers in Conference Proceedings

• Tavares, L., Pimpão, R., Ferreira, R. B. and Santos, C. N. (2010) Phenolics biosynthesis in response to stress conditions in Juniperus sp.. Proceedings of the XXVth International Conference on polyphenols. Montpellier, France, pp. 261-262.
• Pimpão, R., Tavares, L., Oliveira, P., Ferreira R. and Santos C. (2010) Antioxidant properties and nutritional quality assessment of berries produced in Portugal. Proceedings of the XXVth International Conference on polyphenols. Montpellier, France, pp. 448-449.
• Carrilho, D., Tavares, L., Barata, D., Santos, C., Serra, T., Duarte, R., Duarte, C., Espírito-Santo, D., Teixeira, A. and Ferreira, R. (2008) “Antioxidant properties and phytochemical analysis of an uncharacterized Portuguese endemic aromatic herb, Thymus capitellatus. Proceedings of the XXIVth International Conference on Polyphenols, Salamanca, Spain, vol 2 pp. 467-469.
• Santos, C., Duarte, D., Barata, D., Tavares, L., Carrilho, D., Serra, T., Teixeira, A., Duarte, C., Alves, P. and Ferreira, R. (2008) “Phytochemical evaluation of Quercus species- Antioxidant properties of Q. suber leaves in a neurodegeneration cell model. Proceedings of the XXIVth International Conference on polyphenols, Salamanca, Spain, vol 2. pp. 789-791.
• Tavares, L., Barata, D., Santos, C., Carrilho, D., Serra, T., Feliciano, R., Duarte, C., Bronze, R., Oliveira, P. and Ferreira, R. (2008). “Phytochemical characterization of leaf and root tissues from raspberry, including antioxidant activity evaluation. Proceedings of the XXIVth International Conference on Polyphenols, Salamanca, Spain, vol 1 pp. 407-409.