[AVX Seminar] Centrosomes and Cilia in Development and Disease
Mónica Bettencourt-Dias
When |
19 Dec, 2019
from
11:00 am to 12:00 pm |
---|---|
Where | Auditorium ITQB NOVA |
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AVX Seminar
Title: Centrosomes and Cilia in Development and Disease
Speaker: Mónica Bettencourt-Dias
Affiliation: Instituto Gulbenkian de Ciência
The centrosome is an important microtubule-organizing centre (MTOC) in animal cells. It consists of two barrel-shaped structures, the centrioles, surrounded by the pericentriolar material (PCM), which nucleates microtubules. Centrioles can also serve as a template for cilia formation, which plays an important role in signalling and motility. I will focus this talk on the regulation of the centriole structure, in particular on variations in the structure that naturally occur to ensure the formation of different cilia types, as well as variations that occur in disease, and are associated with abnormal cell division.