[IMpaCT Webinar] The cryoEM revolution in structural biology
Professor Richard Henderson
When |
16 Mar, 2021
from
02:30 pm to 03:30 pm |
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Add event to your calendar | iCal |
We would like to invite you to the fourth IMpaCT Seminar to hear Professor Richard Henderson.
The seminar will be held by zoom webinar. Please find the link below:
https://us02web.zoom.us/s/85417861495
Title: The cryoEM revolution in structural biology
Speaker: Professor Richard Henderson, MRC Laboratory of Molecular Biology (Cambridge - UK)
Abstract: In the last 7 years, single particle electron cryomicroscopy (cryoEM) has experienced rapid growth in its capability, due to improved electron microscopes, better detectors and better software, and this is revolutionising structural biology. I will describe some recent results and discuss remaining barriers to progress. CryoEM is already a very powerful method, but there are still many improvements that can be made before the approach reaches its theoretical limits.
Professor Richard Henderson is the Head of the "High resolution 3D structures by electron cryo-microscopy" Lab at the MRC Laboratory of Molecular Biology (Cambridge - UK). Although originally a physicist from Edinburgh University, Professor Henderson switched into molecular biology at the age 21. Since 1973 he began to collaborate with Nigel Unwin and together they developed electron microscopy into a tool for the direct determination of the structure of proteins. This led to the successful determination of the first atomic structure of a membrane protein, bacteriorhodopsin, by using electron microscopy and diffraction. Together with Jacques Dubochet and Joachim Frank, Professor Richard Henderson was given the 2017 Nobel Prize in Chemistry “for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution”, leading the "resolution revolution" that the structural biology field is experiencing.
This series of Seminars are within the scope of "IMpaCT - imaging life from molecules to cells - building knowledge on cryo-electron microscopy methodologies at ITQB NOVA" , and are part of our strategy to bring to ITQB NOVA world-wide renowned scientists in the field of cryo-electron microscopy (cryo-EM), sharing with us their vast experience, and helping us to build a network of connections and knowledge within this area.