[SCAN] Non-invasive measurements it is possible?

SCAN

Title: Non-invasive measurements it is possible?

Speaker: Abel Oliva, ITQB NOVA

Affiliation: Biomolecular Diagnostics Lab

Abstract:

There is a need of biological measurements to be performed in a way that keeps the observation of the object intact. That can be very useful in a wide range of biological studies, from cellular analysis to clinical diagnostics. Studies performed in bulk cell populations are informative; however, they cannot reveal the heterogeneity and molecular dynamics within a certain cell population. Isolation and interrogation of the single cell can provide relevant information related the intrinsic characteristic of the cell, exploring the cell charge polarization, optical properties or even electromagnetic alterations by means of a microfluidic arrangement and electrodes. In the clinical medicine it is also a pressure to perform measurements without affecting the subject (the person). Especially in diseases like diabetes, the need of multiple daily measurements is a limitation that encourages the development of new methods that don´t requires a blood sample. In this presentation it will be discussed the methods developed in our laboratory for non-destructive, single cell analysis and also the new project related the development of a non-invasive blood glucose measurement will be presented and discussed.