[ SCAN ] New 'fragrancies' in hydrogen sulfide metabolism in human biochemistry and (patho)physiology
| When |
05 Jun, 2019
from
12:00 pm to 01:00 pm |
|---|---|
| Where | Auditorium |
| Add event to your calendar |
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Title: New 'fragrancies' in hydrogen sulfide metabolism in human biochemistry and (patho)physiology
Speaker: João Vicente
Affiliation: Structural Genomics, ITQB NOVA
Abstract: Hydrogen sulfide (H2S) has emerged in the biology field from a toxicand smelly chemical to a relevant signaling molecule regulatingnumerous processes. H2S is endogenously synthesized and detoxified byspecialized enzymes and by the gut microbiota. Its physiological rolesare essentially related to its ability to interact with and modify target proteins. Disturbed H2S metabolism has been growingly
associated with multiple human pathologies, from cardiovascular and
neurodegenerative diseases to cancer. Herein I will present an
overview of H2S metabolism, and highlight achievements of our Team on
molecular studies of human H2S metabolism and how they enable
understanding (and targeting) cancer.
