[SCAN] A journey through the world of RNases
Rute Matos
| When |
13 May, 2020
from
12:00 pm to 01:10 pm |
|---|---|
| Where | Zoom Webinar |
| Contact Name | Rita Abranches |
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Title: A journey through the world of RNases
Abstract: Ribonucleases (RNases) are the enzymes that control gene expression by determining the levels of functional RNAs in the cell. They process and degrade all types of RNA and play a central role in the maturation of ribosomal and transfer RNAs, and in RNA quality control. RNases are found in all domains of life, and can be divided into endoribonucleases and exoribonucleases. The combined action of both endo- and exoribonucleases degrades RNAs not needed for the cell and recycles nucleotides to synthesize new RNA. Consequently, RNA degradation is a major mechanism to control gene expression in all organisms. In this seminar I will guide you through the world of RNases and present the work that we have been doing to unveiling the mechanism of action of these proteins. I will focus my presentation in exoribonucleases from the foodborne pathogen Campylobacter jejuni, the major worldwide cause of foodborne gastroenteritis in humans, and how we can use the knowledge obtained to develop new strategies to fight human bacterial pathogens.
Zoom webinar - ITQB NOVA Virtual auditorium
