Architecture of an antimicrobial resistance propagator
Tiago Dias da Costa
| When |
23 Jun, 2022
from
10:00 am to 11:00 am |
|---|---|
| Where | ITQB NOVA Auditorium & Webinar |
| Contact Name | Ana Gomes |
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Title: Architecture of an antimicrobial resistance propagator
Speaker: Tiago Dias da Costa
Affiliation: Imperial College London (UK)
Abstract:
Conjugation is one of the most important processes for the proliferation of antibiotic resistance among bacteria. Central to conjugation is the membrane-embedded type IV secretion system (T4SS) found in both Gram-positive and Gram-negative bacteria. This fascinating multi-task secretion nanomachine is critical for transferring multi-drug resistance plasmids between bacteria and to transport virulence factors to eukaryotic cell targets. I will discuss the exciting recent structural advances in the T4SS field, that are providing novel insights to long-standing questions concerning the dissemination of mobile genetic elements and their cargoes of antibiotic resistance.
You can also participate in the webinar here.
