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iBET researchers interviewed on viral-based vaccines

Conversation about current challenges and benefits of process intensification of viral-based vaccines

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iBET researchers  António Roldão, Cristina Peixoto and Ricardo Silva, joined Alexander Douglas (University of Oxford, UK) and Piergiuseppe Nestola (Sartorius Stedim Biotech, Zug, Switzerland) in a conversation about current challenges and benefits of process intensification of viral-based vaccines. The interview was promoted and moderated by Bioprocess International, highlighting 

  • Why should developers of viral-based vaccines consider process intensification?
  • What are the unique challenges in trying to intensify cell culture for viral-vaccine production?
  • What’s available currently to improve upstream process intensification, and what else is required?
  • At harvest and clarification, what challenges do you face with intensified processing, and how could those be overcome?
  • What other solutions are available downstream?
  • What other factors need to be considered for intensified processing?
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