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Molecular Epidemiology of Staphylococci

Staphylococcus aureus and coagulase-negative staphylococci (CoNS) are responsible for nosocomial and community-acquired infections worldwide. In our laboratory we use several molecular typing techniques to understand the population structure of these pathogens and track their dissemination. The techniques we use include mainly sequenced based methods, like whole genome sequencing, multilocus sequence typing (MLST), spa typing and ccr typing, but also PCR-based methods like SCCmec typing. In addition we use pulsed-field gel electrophoresis (PFGE).

 

   
Research_Molec_Epidem_Staphylococci.jpg   Research_Molec_Epidem_CoNS.jpg   
       

Modulating Staphylococcus aureus cell physiology through a murein ligase. Instituto de Tecnologia Química e Biológica. Universidade Nova de Lisboa, Oeiras, Portugal. ISBN 978-989-20-0523-2. Adapted from Sobral, R.G. 2006. 

 

Analysis of MLST S. epidermidis data by goeBURST algorithm; circles of different colors indicate STs that were found in the hospital and community of both environments. Source: Rolo et al. JAC. 2012.

 

 

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