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[Course] CERMAX practical course on Basic NMR

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When 09 Oct, 2023 12:00 AM to
13 Oct, 2023 12:00 AM
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Short course

The "CERMAX practical course on Basic NMR" is an initiation course to the Nuclear Magnetic Resonance technique with a solid basic theoretical component and a strong practical and theoretical-practical component. The course has a duration of one week starting on a Monday afternoon and ending on the following Friday afternoon with a practical component of 9 hours of use of 500 MHz spectrometers and 13 hours of theoretical and theoretical-practical classes.

The curricular structure includes the following topics: Introduction to NMR spectroscopy-The phenomenon and signal characteristics/information; Instrumental aspects of the spectrometer/Rules for spectrometer use; Sample preparation; 1D Acquisition and processing; Introduction to 2D NMR spectroscopy (Homonuclear correlation); The Nuclear Overhauser Effect; Heteronuclear correlation for small molecule; Protein assignment and structure; The paramagnetic effect and metalloproteins; Residual Dipolar Couplings and disordered proteins; NMR and Metabolomics; Quantitative NMR; and Assignment strategies in small molecules.

Credits: 1.5 ECTS

Target audience

The course is available to all those who need/want basic training in the area of Magnetic Resonance Imaging, but is especially aimed at master's or doctoral students in the life sciences and analytical technicians in the areas of Pharmaceutical Chemistry, Health and Veterinary Sciences. The trainees must have a university degree in the areas of Chemistry and Biology.

Number of participants



From 14 AUG to 08 SEP 

Registration fee: 25€

Enrollment: 15€

Tuition: 750€*

* - Fellowships are available for eligible students, under the PRR regulations (see Official Notice).

Course dates

From 09 to 13 OCT 2023

Evaluation: 20 OCT

Location: ITQB NOVA 

Official Announcement


Luís Gafeira

Helena Matias

Pedro Lamosa

Ricardo Louro

Tiago Cordeiro



14.00 – Introduction to NMR spectroscopy

15.30 – Break

15.50 – Instrumental aspects of the spectrometer/Rules for spectrometer use

16.30 – Spectrometer Guided tour and sample preparation

10 OCT 

9.30 – 1D Acquisition and processing  

10.15 – Introduction to 2D NMR spectroscopy (Homonuclear correlation)
11.00 – Break

11.30 – The Nuclear Overhauser Effect    

12.30 – Lunch break

14.00 – Heteronuclear correlation for small molecule                                   

15.00 – Protein assignment and structure    

11 OCT 

9.30 – The paramagnetic effect and metalloproteins

10.15 – Residual Dipolar Couplings and disordered proteins  

11.00 – Break

11.15 – Practical session  I: Acquisition (1D, presat, p90, APT) | Processing and analyzing 1D

13.30 – Lunch break

14.30 – Practical sessions I (cont)

12 OCT

9.30 – NMR and Metabolomics/Quantitative NMR

11.00 – Break

11.15 – Practical session II Acquisition (COSY, HSQC) | Processing and analyzing 2D

13.30 – Lunch break

14.30 – Practical sessions II (cont)

13 OCT

9.30 – Assignment strategies in small molecules (tutorial and exercises)

10.45 – Break

11.15 – Assignment strategies (cont)

13.00 – Lunch break

14.00 – Practical session III | Acquisition exercises


This course is supported by European funds under the Recovery and Resilience Plan (PRR) of the Portuguese Republic, following the approval of the "CIVIC and GLOBAL" project of Universidade NOVA de Lisboa (RE - C06.i03.03 - Impulso Adultos), through fellowhips for elegible students under the PRR regulations.

The Recovery and Resilience Plan is a nationally applicable programme. The Plan will implement a set of reforms and investments aimed at restoring sustained economic growth, supporting the goal of convergence with Europe over the next decade.

The European Union, faced with the serious impacts of the pandemic on European economies, has created Next Generation EU, a strategic instrument to mitigate the economic and social impact of the crisis; this is capable of promoting economic convergence and resilience, helping to ensure long-term sustainable growth and meeting the challenges of the transition to a greener and more digital society. The Recovery and Resilience Mechanism has been developed on the basis of this instrument, and the RRP fits into this framework.

The RRP is an investment plan for all Portuguese people, based on three structuring dimensions: Resilience; Climate Change; Digital Transition.

More information. 

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