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2023

  1. Jungbluth S, Martin W, Slezak M, Depraetere H, Guzman CA, Ussi A, Morrow D, Van Heuverswyn F, Arnouts S, Carrondo MJT, Olesen O, Ottenhoff THM, Dockrell HM, Ho MM, Dobly A, Christensen D, Segalés J, Laurent F, Lantier F, Stockhofe‑Zurwieden N, Morelli F, Langermans JAM, Verreck FAW, Le Grand R, Sloots A, Medaglini D, Lawrenz M, Collin N. Potential business model for a European vaccine R&D infrastructure and its estimated socio‑economic impact. F1000Research. 2023. 12: 1401. doi:10.12688/f1000research.141399.1
  2. Menzies SK, Arinto‑Garcia R, Amorim FG, Cardoso IA, Abada C, Crasset T, Durbesson F, Edge RJ, El‑Kazzi P, Hall S, Redureau D, Stenner R, Boldrini‑França J, Sun H, Roldão A, Alves PM, Harrison RA, Vincentelli R, Berger I, Quinton L, Casewell NR, Schaffitzel C. ADDovenom: Thermostable Protein‑Based ADDomer Nanoparticles as New Therapeutics for Snakebite Envenoming. Toxins (Basel). 2023 Nov 28; 15(12): 673. doi:10.3390/toxins15120673
  3. Batalha S, Gomes CM, Brito C. Immune microenvironment dynamics of HER2 overexpressing breast cancer under dual anti‑HER2 blockade. Frontiers in Immunology. 2023. 14: 1267621. doi:10.3389/fimmu.2023.1267621
  4. Sebastião MJ, Hoffman M, Escandell J, Tousi F, Zhang J, Figueroa B, DeMaria C, Gomes-Alves P. Identification of mispairing omic signatures in Chinese hamster ovary (CHO) cells producing a tri-specific antibody. Biomedicines. 2023. 11(11): 2890. doi:10.3390/biomedicines11112890
  5. Mooij P, Mortier D, Aartse A, Murad AB, Correia R, Roldão A, Alves PM, Fagrouch Z, Eggink D, Stockhofe N, Engelhardt OG, Verschoor EJ, van Gils MJ, Bogers WM, Carrondo MJT, Remarque EJ, Koopman G. Vaccine-induced neutralizing antibody responses to seasonal influenza virus H1N1 strains are not enhanced during subsequent pandemic H1N1 infection. Frontiers in Immunology. 2023. 14: 1256094. doi:10.3389/fimmu.2023.1256094
  6. Ferreira MV, Fernandes S, Almeida AI, Neto S, Mendes JP, Silva RJS, Peixoto C, Coroadinha AS. Extending AAV packaging cargo through dual co‑transduction: efficient protein trans‑splicing at low vector doses. International Journal of Molecular Sciences. 2023 Jun 23; 24(13): 10524. doi:10.3390/ijms241310524. doi:10.3390/ijms241310524
  7. Neto S, Mendes JP, dos Santos SB, Solbrand A, Carrondo MJT, Peixoto C, Silva RJS. Efficient adeno-associated virus serotype 5 capture with affinity functionalized nanofiber adsorbents. Frontiers in Bioengineering and Biotechnology. 2023 May 16; 11: 1183974. doi:10.3389/fbioe.2023.1183974
  8. Cox MC, Mendes R, Halwachs KN, Domenici G, Brito C, Boghaert ER. Tackling the tumor microenvironment - how can complex tumor models in vitro aid oncology drug development? Expert Opinion on Drug Discovery. 2023 Jul; 18(7): 753–768. doi:10.1080/17460441.2023.2216016
  9. Escandell J, Moura F, Carvalho SB, Silva RJS, Correia R, Roldão A, Gomes-Alves P, Alves PM. Towards a scalable bioprocess for rAAV production using a HeLa stable cell line. Biotechnol Bioeng. 2023 Sep; 120(9): 2578–2587. doi:10.1002/bit.28394
  10. Fernandes S, Diogo J, Coroadinha AS. Mammalian stable cell platforms for recombinant adeno-associated virus (rAAV) production: development strategies and their impact on viral productivity. Curr Gene Ther. 2023; 23(3): 184–197. doi:10.2174/1566523223666230331111336
  11. Meliciano A, Salvador D, Mendonça P, Louro AF, Serra M. Clinically expired platelet concentrates as a source of extracellular vesicles for targeted anti‑cancer drug delivery. Pharmaceutics. 2023. 15(3): 953. doi:10.3390/pharmaceutics15030953
  12. Silva G, Rodrigues AF, Ferreira S, Matos C, Eleutério RP, Marques G, Kucheryava K, Lemos AR, Sousa PMF, Castro R, Barbas A, Simão D, Alves PM. Novel scFv against Notch Ligand JAG1 Suitable for Development of Cell Therapies toward JAG1-Positive Tumors. Biomolecules. 2023. 13(3): 459. doi:10.3390/biom13030459
  13. Silvano M, Virgolini N, Correia R, Clarke C, Isidro IA, Alves PM, Roldão A. Dissecting insect cell heterogeneity during influenza VLP production using single‑cell transcriptomics. Frontiers in Bioengineering and Biotechnology. 2023. 11: 143255. doi:10.3389/fbioe.2023.1143255
  14. Virgolini N, Silvano M, Hagan R, Correia R, Alves PM, Clarke C, Roldão A, Isidro IA. Impact of dual‑baculovirus infection on the Sf9 insect cell transcriptome during rAAV production using single‑cell RNA‑seq. Biotechnology and Bioengineering. 2023. 120(9): 2588–2600. doi:10.1002/bit.28377
  15. Costa MHG, Costa MS, Painho B, Sousa CD, Carrondo I, Oltra E, Pelacho B, Prosper F, Isidro IA, Alves P, Serra M. Enhanced bioprocess control to advance the manufacture of mesenchymal stromal cell‑derived extracellular vesicles in stirred‑tank bioreactors. Biotechnology and Bioengineering. 2023 Sep; 120(9): 2725–2741. doi:10.1002/bit.28378
  16. Coroadinha AS. Host cell restriction factors blocking efficient vector transduction: challenges in lentiviral and adeno-associated vector based gene therapies. Cells. 2023. 12(5): 732. doi:10.3390/cells12050732
  17. Moreira AS, Bezemer S, Faria TQ, Detmers F, Hermans P, Sierkstra L, Coroadinha AS, Peixoto C. Implementation of novel affinity ligand for lentiviral vector purification. International Journal of Molecular Sciences. 2023 Feb 8; 24(4): 3354. doi:10.3390/ijms24043354
  18. Virgolini N, Hagan R, Correia R, Silvano M, Fernandes S, Alves PM, Clarke C, Roldão A, Isidro IA. Transcriptome analysis of Sf9 insect cells during production of recombinant adeno‑associated virus. Biotechnology Journal. 2022; 18(2): e2200466. doi:10.1002/biot.2022004664
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