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2025

  1. Gal IR, Demarta-Gatsi C, Fontinha D, Arez F, Wicha SG, Rottmann M, Nunes-Cabaço H, Blais J, Jain JP, Lakshminarayana SB, Brito C, Prudêncio M, Alves PM, Spangenberg T. Drug Interaction Studies of Cabamiquine:Ganaplacide Combination against Hepatic Plasmodium berghei. ACS Infect Dis. 2025 Jan 10;11(1):69-79. doi: 10.1021/acsinfecdis.4c00563
  2. Nascimento A, Faria TQ, Bollmann F, Noverraz M, Pressac G, Roldão A, Peixoto C, Silva RJS. Purification of AAV8 through a scalable two-step monolithic chromatography approach. J Chromatogr A. 2025 Jan 11;1740:465586. doi: 10.1016/j.chroma.2024.465586
  3. Arez F, Preiss L, Gal IR, Rebelo SP, Badolo L, Brito C, Spangenberg T, Alves PM. Heterotypic spheroids as a strategy for 3D culture of cryopreserved primary human hepatocytes in stirred-tank systems. SLAS Discov. 2025 Mar;31:100210. doi: 10.1016/j.slasd.2025.100210
  4. Correia R, Zotler T, Ferraz F, Fernandes B, Graça M, Pijlman GP, Alves PM, Roldão A. Continuous Production of Influenza VLPs Using IC-BEVS and Multi-Stage Bioreactors. Biotechnol Bioeng. 2025;122(4):846-857. doi: 10.1002/bit.28925
  5. Vicente P, Inocêncio LR, Ullate-Agote A, Louro AF, Jacinto J, Gamelas B, Iglesias-García O, Martin-Uriz PS, Aguirre-Ruiz P, Ríos-Muñoz GR, Fernández-Santos ME, van Mil A, Sluijter JPG, Prósper F, Vega MMM, Alves PM, Serra M. Billion-Scale Expansion of Functional hiPSC-Derived Cardiomyocytes in Bioreactors Through Oxygen Control and Continuous Wnt Activation. Adv Sci (Weinh). 2025 Mar;12(11):e2410510. doi: 10.1002/advs.202410510
  6. Abbo SR, Yan K, Geertsema C, Hick TAH, Altenburg JJ, Nowee G, van Toor C, van Lent JW, Nakayama E, Tang B, Metz SW, Bhowmik R, de Silva AM, Prow NA, Correia R, Alves PM, Roldão A, Martens DE, van Oers MM, Suhrbier A, Pijlman GP. Virus-like particle vaccine with authentic quaternary epitopes protects against Zika virus-induced viremia and testicular damage. J Virol. 2025; 99(4):e0232224. doi: 10.1128/jvi.02322-24
  7. Costa MS, Costa CM, Matos LN, Sebastião MJ, Duarte N, Costa MHG, Serra M. Controlled activation modulates T-cell expansion and phenotype in stirred-tank bioreactors. Cytotherapy. 2025 Jun;27(6):774-781. doi: 10.1016/j.jcyt.2025.02.003
  8. Formas-Oliveira AS, Ferreira MV, Coroadinha AS. Deciphering key parameters enhancing lentiviral vector producer cells yields: Vector components copy number and expression. Mol Ther Methods Clin Dev. 2025 Feb 10;33(1):101431. doi: 10.1016/j.omtm.2025.101431
  9. Fernandes S, Guerra J, Ferreira MV, Coroadinha AS. Deciphering Key Adenoviral Elements in the Production of Recombinant Adeno-Associated Virus Vectors. Hum Gene Ther. 2025 Apr 22. doi: 10.1089/hum.2024.265
  10. van Oosten L, Altenburg JJ, Nowee G, Kenbeek D, Neef T, Rouw T, Tegelbeckers VIP, van der Heijden J, Mentink S, Willemsen W, Hausjell CS, Kuijpers L, van der Pol L, Roldão A, Correia R, van den Born E, Wijffels RH, Martens DE, van Oers MM, Pijlman GP. Engineered thermoswitch in the baculovirus expression vector system for production of virus-like particle vaccines with minimized baculovirus contaminants. Trends Biotechnol. 2025 Jul;43(7):1690-1713. doi: 10.1016/j.tibtech.2025.04.004
  11. Jardim C, Bica M, Reis-Sobreiro M, Teixeira da Mota A, Lopes R, Pinto MF, Sousa NS, Mensurado S, Boekhoff H, Scolaro T, Reugebrink M, Goncalves-Sousa N, Kubo H, Gomes CM, Brito C, Argüello RJ, Leites EP, Morais VA, Silva-Santos B, Barbosa-Morais NL, Serre K. Sustained Macrophage Reprogramming Is Required for CD8+ T cell-Dependent Long-Term Tumor Eradication. Cancer Immunol Res. 2025 Aug 1;13(8):1207-1225. doi: 10.1158/2326-6066.CIR-24-0797
  12. Dias MM, Carvalho SB, Matheise JP, Van Beersel G, Knott I, Gomes-Alves P, Alves PM. High-throughput flow cytometry-based titration of a live attenuated rotavirus vaccine. J Biotechnol. 2025 Jul 3;406:91-98. doi: 10.1016/j.jbiotec.2025.07.004
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