Biological Chemistry
The Biological Chemistry division of ITQB NOVA uses biochemical and biophysical methods to investigate the molecular mechanisms of biological processes relevant to health and sustainability
The Biological Chemistry division has a strong focus on functional and structural characterisation of proteins, in particular metalloproteins, membrane proteins and proteins related to human health, and also an important program on cellular stress responses. The biological problems addressed range from biological energy conservation in aerobic and anaerobic microorganisms to mechanisms of oxidative and nitrosative stress responses used by pathogens to evade host immune defenses, and also responses to metal and metalloid stress. Other studies include protein folding and stability, protein modelling and development of theoretical/computational methods for the simulation of biomolecular systems. More applied studies target the structural characterisation of proteins with pharmacological or health importance, and of enzymes with biotechnological applications
Biological Chemistry division groups are part of MOSTMICRO-ITQB research Unit or INOVA4HEALTH research unit.
Head of Division: Pedro Matias
Laboratories
- Antonio M. Baptista Lab - Molecular Simulation
- Carlos Frazão Lab - Structural Biology
Macromolecular Crystallography Unit - Claudina R. Pousada Lab - Genomics and Stress Laboratory
- Cláudio M. Soares Lab - Protein Modeling
- Colin McVey Lab - Structural Virology
Macromolecular Crystallography Unit - Inês Cardoso Pereira Lab - Bacterial Energy Metabolism
- Ligia M. Saraiva Lab - Molecular Mechanisms of Pathogen Resistance
- Ligia O. Martins Lab - Microbial & Enzyme Technology
- Manuela M. Pereira Lab - Biological Energy Transduction
Metalloproteins and Bioenergetics Unit - Manuel N. Melo Lab - Multiscale Modeling
- Margarida Archer Lab - Membrane Protein Crystallography
Macromolecular Crystallography Unit - Maria Arménia Carrondo Lab - Structural Genomics
Macromolecular Crystallography Unit - Miguel Teixeira Lab - Metalloenzymes and Molecular Bioenergetics
Metalloproteins and Bioenergetics Unit - Pedro Matias Lab - Industry and Medicine Applied Crystallography
Macromolecular Crystallography Unit - Ricardo O. Louro Lab - Inorganic Biochemistry and NMR
- Smilja Todorovic Lab - Raman BioSpectroscopy
- Tiago N. Cordeiro Lab - Dynamic Structural Biology







