Sustainable Catalytic Methods for Organic Synthesis
Duration: 4 weeks to 12 months depending on the type of internship (Duration can be extended to suit the interest of potential candidates)
Detalhes
BACKGROUND
The conservation of our natural resources is a fundamental challenge of mankind. New catalytic systems based on Earth-abundant and nontoxic transition metals that allow rapid and selective chemical transformations through atom-economy processes will have a significant impact in our society.
OBJECTIVES
The present project aims to develop of a new generation of highly efficient phosphine-free metal-based catalysts with tunable reactivity for the synthesis of valuable organic molecules through atom-economy methods. This project will allow students to receive laboratory training in the synthesis of organometallic compounds (working under inert atmosphere conditions-Schlenk-line methodology) and organic synthesis, as well as in the characterization of chemical compounds (NMR, IR, MS, etc.).This project will involve the synthesis of metal complexes (Fe, Mn, Ni, Co, Cu) complexes bearing N-heterocyclic carbene ligands (NHCs) and their application as catalysts for a variety of catalytic reactions. In particular, in Acceptorless Dehydrogenation and Borrowing Hydrogen Processes for the preparation of pharmaceutically relevant targets.
